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Survivin Suppression Strengthens BZML-induced Mitotic Catastrophe to Overcome Multidrug Resistance by Removing Senescent A549/Taxol Cells

Zhaoshi Bai、Yiran Zhou、Xinyue Ye 等 6 位作者2020-08-17Research Square

Abstract Background: Mitotic catastrophe (MC) of cancer cells induced by BZML, a novel colchicine-binding site inhibitor, exerts a significant advantage in overcoming multidrug resistance (MDR) in NSCLC. However, the long cellular death process resulting from MC is not beneficial for anticancer treatment. Here, we stu…

Nanoparticle-Based Drug DeliveryAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene Delivery

Dự đoán sự tiêu tán áp lực nước lỗ rỗng của bài toán bấc thấm (bài toán 1D)

Nguyễn Trọng Nghĩa2020-08-17TẠP CHÍ KHOA HỌC ĐẠI HỌC MỞ THÀNH PHỐ HỒ CHÍ MINH - KỸ THUẬT VÀ CÔNG NGHỆ

Bấc thấm (PVD) được sử dụng khá rộng rãi trong việc thúc đẩy nhanh quá trình cố kết trong đất yếu, qua đó tăng cường tính chất của đất và giảm lún. Giải bài toán cố kết của bấc thấm được giải bằng nhiều phương pháp khác nhau như: Phương pháp giải tích, Phương pháp sai phân hữu hạn và phương pháp phần tử hữu hạn. Trong…

Structural mechanics and materialsGeodetic Measurements and Engineering Structures

Assembly of Gentamicin and Zn2+ Loaded Coatings on TiO2 Nanotubes to Synergistically Improve the Blood Compatibility, Endothelial Cell Growth and Antibacterial Activities

Changjiang Pan、Ya Yang、Youdong Hu 等 8 位作者2020-08-17Research Square

Abstract Titanium and its alloys are widely used in blood contacting implantable and interventional medical devices; however, their biocompatibility is still facing great challenges. In this study, with the aim of improving the biocompatibility and antibacterial activities of titanium, TiO2 nanotubes with a diameter o…

Bone Tissue Engineering MaterialsElectrospun Nanofibers in Biomedical ApplicationsPolymer Surface Interaction Studies

Energy Barrier Analysis of High Density Hamr Simulations

Eric Roddick、Lei Xu、Richard M. Brockie2020-08-17OpenAlex

Some form of heat assistance is likely to be required to achieve >3Tbpsi recording density and continue the long progression of capacity growth of magnetic recording in hard disk drives. To provide useful component design guidance, micromagnetic simulations of heat assisted magnetic recording (HAMR) must include estim…

Magnetic properties of thin filmsPhase-change materials and chalcogenidesAdhesion, Friction, and Surface Interactions

Molybdenum Trioxide on Anatase TiO2(101) - Formation of Monodispersed (MoO3)1 Monomers from Oligomeric (MoO3)n Clusters

Nassar Doudin、Greg Collinge、Pradeep Kumar 等 7 位作者2020-08-17ChemRxiv

Complex oxide systems with hierarchical order are of critical importance in material science and catalysis. Despite their immense potential, their design and synthesis are rather difficult. In this study we demonstrate how the deposition of small oligomeric (MoO 3 ) 1-6 clusters, which can be formed by the sublimation…

Catalytic Processes in Materials ScienceCatalysis and Hydrodesulfurization StudiesCatalysis and Oxidation Reactions

Scattering of magnons at graphene quantum-Hall-magnet junctions

Nemin Wei、Chunli Huang、A. H. MacDonald2020-08-17arXiv (Cornell University)

Motivated by recent non-local transport studies of quantum-Hall-magnet (QHM) states formed in monolayer graphene's $N=0$ Landau level, we study the scattering of QHM magnons by gate-controlled junctions between states with different integer filling factors $ν$. For the $ν=1|-1|1$ geometry we find magnons are weakly sc…

Magnetic properties of thin filmsGraphene research and applicationsQuantum and electron transport phenomena

Influence des paramètres de trempe sur l’évolution des propriétés thermo-physiques de l’acier 300M

Romain Alcaras2020-08-17Espace ÉTS (ETS)

Les aciers subissent de nombreux traitements thermiques pour atteindre des propriétés mécaniques ciblées. L'acier 300M est ainsi utilisé pour la fabrication des trains d'atterrissage à l'état trempé-revenu. Le traitement thermique de trempe martensitique puis revenu est appliqué sur les pièces juste avant les phases f…

Microstructure and Mechanical Properties of SteelsMetallurgy and Material FormingMetal Alloys Wear and Properties

Comportamiento electroquímico de los aceros 316L, 316L nitrurado y F1586 en fluido corporal simulado

Diana Shirley Galeano Osorio、Santiago Vargas Giraldo、Juan Manuel Vélez2020-08-17Revista EIA

Los materiales metálicos se emplean con frecuencia en la fabricación de implantes biomédicos, siendo la corrosión un factor que determina el éxito del desempeño del implante en el organismo. Debido a esto, en la presente investigación se estudió el comportamiento electroquímico de los aceros 316L, 316L nitrurado y F15…

Metal and Thin Film MechanicsOrthopaedic implants and arthroplastyHydrogen embrittlement and corrosion behaviors in metals

Issues using equivalent circuit elements to describe trapped ions

Noah Van Horne、M. Mukherjee2020-08-17arXiv (Cornell University)

Trapped charged particles, and in particular trapped ions, are among the leading candidates for quantum computing technologies. However, our ability to interconnect arrays of ions in different traps is a significant hurdle in scaling trapped ion quantum computing. One approach to overcome this problem is using a solid…

Quantum Information and CryptographyQuantum and electron transport phenomenaElectronic and Structural Properties of Oxides

316L Stainless Steel Sensitization in Carbon Nanotube CVD Growth for Bacterial Resistance

Sterling Voss、Bret Mecham、Lucy C. Bowden 等 6 位作者2020-08-17OpenAlex

Abstract Physically altering the micro-topography of a surface can dramatically affect its capacity to support or prevent biofilm growth. Growing carbon-infiltrated carbon nanotubes on biomedical materials is one such approach which has proven effective. Unfortunately, the high temperature and carbon-rich gas exposure…

Carbon Nanotubes in CompositesMetal and Thin Film MechanicsElectrohydrodynamics and Fluid Dynamics

Design and Optimization of Functionally Graded Superelastic NiTi Stents

Jivtesh B. Khurana、Mary Frecker、Eric M. Pauli2020-08-17OpenAlex

Abstract Endoscopic stents are being used by surgeons in off-label uses to manage leaks and perforations in the gastrointestinal tract. Commercially available stents are primarily designed to open strictures in the esophagus through tissue compression. The stents incorporate a woven NiTi wire to produce a stiff and li…

Shape Memory Alloy TransformationsAdvanced Materials and MechanicsStructural Engineering and Vibration Analysis

Design Framework for Multi-Section Shape Memory Alloy Axial Actuators Considering Material and Geometric Uncertainties

Weilin Guan、Edwin A. Peraza Hernandez2020-08-17OpenAlex

Abstract Shape memory alloys are metallic materials with the capability of performing as high energy density actuators driven by temperature control. This paper presents a design framework for shape memory alloy (SMA) axial actuators composed of multiple wire sections connected in series. The various wire sections for…

Shape Memory Alloy TransformationsTopology Optimization in EngineeringStructural Engineering and Vibration Analysis

Basic Performance of Natural Fiber Bevel Gears Made From Only Bamboo Fibers Extracted With a Machining Center

Tetsuya Kawabata、Toshiki HIROGAKI、Eiichi AOYAMA 等 5 位作者2020-08-17OpenAlex

Abstract Metal gears can transmit large torque. The disadvantages associated with metal gears are the noise produced and necessity of lubricants. Plastic gears are advantageous because they are lightweight and can be used without lubricants. However, plastic gears have relatively low strengths and damaging environment…

Natural Fiber Reinforced CompositesBamboo properties and applications

Finite Element Models for Flexible Cosserat Solids

Olivier A. Bauchau、Minghe Shan2020-08-17OpenAlex

Abstract The application of the finite element method to the modeling of Cosserat solids is investigated in detail. In two- and three-dimensional elasticity problems, the nodal unknowns are the components of the displacement vector, which form a linear field. In contrast, when dealing with Cosserat solids, the nodal u…

Elasticity and Material ModelingNonlocal and gradient elasticity in micro/nano structuresGeophysics and Sensor Technology

Nonlinear Dynamic Response of an Isolation System With Negative Stiffness and Shape Memory-Based Damping

Andrea Salvatore、Biagio Carboni、Walter Lacarbonara2020-08-17OpenAlex

Abstract The negative stiffness offered by bi-stable mechanisms can improve the dynamic performance of a structure. In this work the effects of adding negative stiffness and shape memory alloy (SMA) damping in base-isolated structures are explored through the study of the stationary response for different values of ne…

Vibration Control and Rheological FluidsShape Memory Alloy TransformationsStructural Engineering and Vibration Analysis

Elastic and Inelastic Electron-Nucleus Scattering Form Factors for Be9 Nucleus

Hawar Muhamad Dlshad、Aziz H. Fatah、Adil Mohammed Hussain2020-08-17UHD Journal of Science and Technology

The computations of the elastic and inelastic Coulomb form factors for the electron-nucleus scattering of Beryllium nucleus Be9 have performed with Core Polarization (CP) effects including the realistic Michigan sum of Three Range Yukawa (M3Y) Interaction, and the other residual interaction which is Modified Surface D…

Atomic and Molecular PhysicsElectron and X-Ray Spectroscopy TechniquesMuon and positron interactions and applications

Dataset associated with the manuscript titled "Capturing non-local through-bond effects when fragmenting molecules for quantum chemical torsion scans"

Chaya Stern、Christopher I. Bayly、Daniel G. A. Smith 等 7 位作者2020-08-17Zenodo (CERN European Organization for Nuclear Research)

The dataset is a part of the supporting information of the fragmenter manuscript, which also describes how this dataset was generated in more detail. This dataset includes all fragments generated from 730 FDA approved molecule without fragmenting rings. Scripts used to generate this set live here. 1. Filter DrugBank w…

Machine Learning in Materials ScienceNuclear Physics and ApplicationsQuantum, superfluid, helium dynamics

Clarification on “Critical Comments on ‘Assessment of the Thermodynamic Properties of DL-p-Mentha-1,8-diene, 4-isopropyl-1-methylcyclohexene (DL-Limonene) by Inverse Gas Chromatography (IGC)’”

Negin Farshci、A. Abbasian2020-08-17Journal of Chromatographic Science

A clarification is given regarding recent polemic over our original published study. The author of this polemic has claimed a few issues about the computations and data listed in our work such as choosing the wrong temperature unit and the incorrect calculation of molar heat of vaporization. Here it is elaborated the…

Thermal and Kinetic AnalysisChemical Thermodynamics and Molecular StructureAdsorption, diffusion, and thermodynamic properties of materials