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PLGA-PEG-ANG-2 Nanoparticles for Blood–Brain Barrier Crossing: Proof-of-Concept Study

Gina P. Hoyos-Ceballos、Barbara Ruozi、Ilaria Ottonelli 等 12 位作者2020-01-17Pharmaceutics

The treatment of diseases that affect the central nervous system (CNS) represents a great research challenge due to the restriction imposed by the blood–brain barrier (BBB) to allow the passage of drugs into the brain. However, the use of modified nanomedicines engineered with different ligands that can be recognized…

Nanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsSupramolecular Self-Assembly in Materials

Singular charge fluctuations at a magnetic quantum critical point

L. Prochaska、Xinwei Li、D. C. MacFarland 等 15 位作者2020-01-17Science

Spin-charge entanglement Many physical properties follow characteristic scaling laws near quantum critical points, which are associated with phase transitions at absolute zero temperature. The material YbRh 2 Si 2 has an antiferromagnetic quantum critical point, where spin-related properties are expected to follow suc…

Physics of Superconductivity and MagnetismRare-earth and actinide compoundsIron-based superconductors research

Proliferation of Faulty Materials Data Analysis in the Literature

Matthew R. Linford、Vincent S. Smentkowski、John T. Grant 等 22 位作者2020-01-17Microscopy and Microanalysis

As a group of subject-matter experts in X-ray photoelectron spectroscopy (XPS) and other material characterization techniques from different countries and institutions, we write this document to raise awareness of an epidemic of poor and incorrect materials data analysis in the literature. This issue is a growing prob…

Metallurgical Processes and ThermodynamicsMachine Learning in Materials ScienceMineral Processing and Grinding

Shape-morphing living composites

Laura K. Rivera‐Tarazona、V. D. Bhat、Hyun Kim 等 5 位作者2020-01-17Science Advances

). These living, shape-changing materials may enable sensors or medical devices that respond to highly specific cues found within a biological milieu.

Advanced Sensor and Energy Harvesting MaterialsAdvanced Materials and MechanicsSilk-based biomaterials and applications

Multivariate Modulation of the Zr MOF UiO‐66 for Defect‐Controlled Combination Anticancer Drug Delivery

Isabel Abánades Lázaro、Connor J. R. Wells、Ross S. Forgan2020-01-17Angewandte Chemie

Abstract Metal–organic frameworks (MOFs) are emerging as leading candidates for nanoscale drug delivery, as a consequence of their high drug capacities, ease of functionality, and the ability to carefully engineer key physical properties. Despite many anticancer treatment regimens consisting of a cocktail of different…

Metal-Organic Frameworks: Synthesis and ApplicationsBoron and Carbon Nanomaterials ResearchX-ray Diffraction in Crystallography

Synergistically Chemical and Thermal Coupling between Graphene Oxide and Graphene Fluoride for Enhancing Aluminum Combustion

Yue Jiang、Sili Deng、Sungwook Hong 等 11 位作者2020-01-17ACS Applied Materials & Interfaces

Metal combustion reaction is highly exothermic and is used in energetic applications, such as propulsion, pyrotechnics, powering micro- and nano-devices, and nanomaterials synthesis. Aluminum (Al) is attracting great interest in those applications because of its high energy density, earth abundance, and low toxicity.…

Energetic Materials and CombustionFullerene Chemistry and ApplicationsThermal and Kinetic Analysis

Tuning Cellular Biological Functions Through the Controlled Release of NO from a Porous Ti‐MOF

Rosana V. Pinto、Sujing Wang、Sérgio R. Tavares 等 11 位作者2020-01-17Angewandte Chemie International Edition

Abstract Materials for the controlled release of nitric oxide (NO) are of interest for therapeutic applications. However, to date, many suffer from toxicity and stability issues, as well as poor performance. Herein, we propose a new NO adsorption/release mechanism through the formation of nitrites on the skeleton of a…

Metal-Organic Frameworks: Synthesis and ApplicationsCatalytic Processes in Materials ScienceAdvanced Nanomaterials in Catalysis

Al-rich AlGaN based transistors

Albert G. Baca、Andrew Armstrong、Brianna Klein 等 6 位作者2020-01-17Journal of Vacuum Science & Technology A Vacuum Surfaces and Films

Research results for AlGaN-channel transistors are reviewed as they have progressed from low Al-content and long-channel devices to Al-rich and short-channel RF devices. Figure of merit (FOM) analysis shows encouraging comparisons relative to today’s state-of-the-art GaN devices for high Al-content and elevated temper…

GaN-based semiconductor devices and materialsSilicon Carbide Semiconductor TechnologiesGa2O3 and related materials

Seeing is believing: visualization of antiferromagnetic domains

Sang-Wook Cheong、M. Fiebig、Weida Wu 等 5 位作者2020-01-17npj Quantum Materials

Abstract Understanding and utilizing novel antiferromagnetic (AFM) materials has been recently one of the central issues in condensed matter physics, as well as in materials science and engineering. The relevant contemporary topics include multiferroicity, topological magnetism and AFM spintronics. The ability to imag…

Physics of Superconductivity and MagnetismMagnetic properties of thin filmsMultiferroics and related materials

Targeted camptothecin delivery via silicon nanoparticles reduces breast cancer metastasis

Marietta Landgraf、Christoph A. Lahr、Ishdeep Kaur 等 12 位作者2020-01-17Biomaterials

In advanced breast cancer (BCa) patients, not the primary tumor , but the development of distant metastases , which occur mainly in the organ bone, and their adverse health effects are responsible for high mortality. Targeted delivery of already known drugs which displayed potency, but rather unfavorable pharmacokinet…

Advanced biosensing and bioanalysis techniquesNanoplatforms for cancer theranosticsBoron and Carbon Nanomaterials Research

Magnetism and anomalous transport in the Weyl semimetal PrAlGe: possible route to axial gauge fields

D. Destraz、Lakshmi Kanta Das、Stepan S. Tsirkin 等 13 位作者2020-01-17npj Quantum Materials

Abstract In magnetic Weyl semimetals, where magnetism breaks time-reversal symmetry, large magnetically sensitive anomalous transport responses are anticipated that could be useful for topological spintronics. The identification of new magnetic Weyl semimetals is therefore in high demand, particularly since in these s…

Graphene research and applicationsCold Atom Physics and Bose-Einstein CondensatesTopological Materials and Phenomena

Comparison of Three Xylose Pathways in Pseudomonas putida KT2440 for the Synthesis of Valuable Products

Isabel Bator、Andreas Wittgens、Frank Rosenau 等 5 位作者2020-01-17Frontiers in Bioengineering and Biotechnology

Pseudomonas putida KT2440 is a well-established chassis in industrial biotechnology. To increase the substrate spectrum, we implemented three alternative xylose utilization pathways, namely the Isomerase, Weimberg, and Dahms pathways. The synthetic operons contain genes from Escherichia coli and Pseudomonas taiwanensi…

Biofuel production and bioconversionMicrobial Metabolic Engineering and BioproductionEnzyme Structure and Function

Ni-Mn catalysts on silica-modified alumina for CO2 methanation

Wilbert L. Vrijburg、Gabriella Garbarino、Wei Chen 等 7 位作者2020-01-17Journal of Catalysis

The viability of the Power-to-Gas (PtG) concept is strongly dependent on the development of highly active and stable methanation catalysts obtained from cheap and abundant elements. In this paper, the promotional effect of MnO on Ni catalysts supported on silica-modified γ-Al2O3 (SA) was investigated in CO2 and CO met…

Catalytic Processes in Materials ScienceCatalysts for Methane ReformingCarbon dioxide utilization in catalysis

Light-degradable hydrogels as dynamic triggers for gastrointestinal applications

Ritu Raman、Tiffany Hua、Declan Gwynne 等 12 位作者2020-01-17Science Advances

Triggerable materials capable of being degraded by selective stimuli stand to transform our capacity to precisely control biomedical device activity and performance while reducing the need for invasive interventions. Here, we describe the development of a modular and tunable light-triggerable hydrogel system capable o…

Hydrogels: synthesis, properties, applicationsElectrospun Nanofibers in Biomedical Applications3D Printing in Biomedical Research

Insertion of HfO2 Seed/Dielectric Layer to the Ferroelectric HZO Films for Heightened Remanent Polarization in MFM Capacitors

V. Gaddam、Dipjyoti Das、Sanghun Jeon2020-01-17IEEE Transactions on Electron Devices

This article highlights the role of HfO2seed/dielectric insertion layers on the ferroelectric properties of hafnium zirconium oxide (HZO)-based metal-ferroelectric-metal (MFM) capacitors. Maximum remanent polarization (Pr) of 22.1 μC/cm2was achieved when HfO2seed layer of critical thickness (10 Å) was inserted at the…

Semiconductor materials and devicesMXene and MAX Phase MaterialsFerroelectric and Negative Capacitance Devices

Self-Assembled FRET Nanoprobe with Metal–Organic Framework As a Scaffold for Ratiometric Detection of Hypochlorous Acid

Hongliang Tan、Xiayi Wu、Yuhao Weng 等 5 位作者2020-01-17Analytical Chemistry

Metal-organic framework (MOF) has been extensively explored in a number of fields due to its diverse properties. In this work, we demonstrated the potential of MOF in the establishment of a self-assembled fluorescence resonance energy transfer (FRET) system for developing ratiometric fluorescent nanoprobe. For this pu…

Molecular Sensors and Ion DetectionCarbon and Quantum Dots ApplicationsAdvanced Nanomaterials in Catalysis

Review of Chitosan-Based Polymers as Proton Exchange Membranes and Roles of Chitosan-Supported Ionic Liquids

Nur Adiera Hanna Rosli、Kee Shyuan Loh、Wai Yin Wong 等 7 位作者2020-01-17International Journal of Molecular Sciences

Perfluorosulphonic acid-based membranes such as Nafion are widely used in fuel cell applications. However, these membranes have several drawbacks, including high expense, non-eco-friendliness, and low proton conductivity under anhydrous conditions. Biopolymer-based membranes, such as chitosan (CS), cellulose, and carr…

Fuel Cells and Related MaterialsConducting polymers and applicationsAdvanced battery technologies research

Photopolymer Resins with Biobased Methacrylates Based on Soybean Oil for Stereolithography

Jarno Guit、Marjory B.L. Tavares、Jerzy Hul 等 8 位作者2020-01-17ACS Applied Polymer Materials

The accessibility of renewable materials that are both sustainable and competitive is essential to accommodate the rapid growth in consumption of 3D printing materials. We have developed biobased photopolymer resins based on modified soybean oil for application in commercial stereolithography printers. First, soybean…

biodegradable polymer synthesis and propertiesAdditive Manufacturing and 3D Printing TechnologiesPhotopolymerization techniques and applications

Highly Stable Zinc-Based Metal–Organic Frameworks and Corresponding Flexible Composites for Removal and Detection of Antibiotics in Water

Shuang Gai、Jian Zhang、Ruiqing Fan 等 10 位作者2020-01-17ACS Applied Materials & Interfaces

Antibiotic contamination of water bodies is a major environmental concern. Exposure to superfluous antibiotics is an ecological stressor correlated to the development of antibiotic resistance. Thus, it is imperative that effective methods are developed to simultaneously detect and remove such antibiotics so as to avoi…

Advanced Photocatalysis TechniquesMetal-Organic Frameworks: Synthesis and ApplicationsCovalent Organic Framework Applications

Plasmon–emitter interactions at the nanoscale

P. A. D. Gonçalves、Thomas Christensen、Nicholas Rivera 等 6 位作者2020-01-17Nature Communications

Plasmon-emitter interactions are of central importance in modern nanoplasmonics and are generally maximal at short emitter-surface separations. However, when the separation falls below 10-20 nm, the classical theory deteriorates progressively due to its neglect of quantum effects such as nonlocality, electronic spill-…

Gold and Silver Nanoparticles Synthesis and ApplicationsPlasmonic and Surface Plasmon ResearchNanowire Synthesis and Applications