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Bio-inspired protein–gold nanoconstruct with core–void–shell structure: beyond a chemo drug carrier

Xiangyou Liu、Wei Wei、Shijiao Huang 等 11 位作者2013-04-23Journal of Materials Chemistry B

Chemotherapy has been widely used in clinical practice for cancer treatment. A major challenge for a successful chemotherapy is to potentiate the anticancer activity, whilst reducing the severe side effects. In this context, we design a bio-inspired protein–gold nanoconstruct (denoted as AFt–Au hereafter) with a core–…

Nanoparticle-Based Drug DeliveryAdvanced biosensing and bioanalysis techniquesNanocluster Synthesis and Applications

Structure and function ofEscherichia coliRimK, an ATP-grasp fold,l-glutamyl ligase enzyme

Gengxiang Zhao、Zhongmin Jin、Yanli Wang 等 6 位作者2013-04-23Proteins Structure Function and Bioinformatics

We report herein the crystal structure of Escherichia coli RimK at a resolution of 2.85 Å, an enzyme that catalyzes the post-translational addition of up to 15 C-terminal glutamate residues to ribosomal protein S6. The structure belongs to the ATP-grasp superfamily and is organized as a tetramer, consistent with gel f…

RNA and protein synthesis mechanismsGlycosylation and Glycoproteins ResearchEnzyme Structure and Function

Uniform magnetization transfer in chemical exchange saturation transfer magnetic resonance imaging

Jae‐Seung Lee、Prodromos Parasoglou、Ding Xia 等 5 位作者2013-04-23Scientific Reports

The development of chemical exchange saturation transfer (CEST) has led to the establishment of new contrast mechanisms in magnetic resonance imaging, which serve as enablers for advanced molecular imaging strategies. Macromolecules in tissues and organs often give rise to broad and asymmetric exchange effects, called…

Advanced MRI Techniques and ApplicationsLanthanide and Transition Metal ComplexesMRI in cancer diagnosis

Synergistic Effects of Montmorillonite/Cerium Nitrate Additives on the Corrosion Performance of Epoxy-Clay Nanocomposite Coatings

E. Darmiani、Gholamreza Rashed、Davood Zaarei 等 4 位作者2013-04-23Polymer-Plastics Technology and Engineering

In this work, different amounts of montmorillonite were added to cerium nitrate epoxy mixture. Nanocomposite coatings containing cerium nitrate were applied on cold rolled steel panels. The state of dispersion and incorporation were characterized by transmission electron microscopy and atomic force microscopy. To inve…

Corrosion Behavior and InhibitionPolymer Nanocomposites and PropertiesPolymer Nanocomposite Synthesis and Irradiation

Biological activity and magnetic resonance imaging of superparamagnetic iron oxide nanoparticles-labeled adipose-derived stem cells

Jingjing Fan、Yanbin Tan、Liyong Jie 等 6 位作者2013-04-23Stem Cell Research & Therapy

INTRODUCTION: No comparative study of adipose-derived stem cells (ADSCs) and bone marrow mesenchymal stem cells (BMSCs) by using superparamagnetic iron oxide nanoparticles (SPIOs)-labeling and magnetic resonance imaging (MRI) has been performed. METHODS: We studied the biological activity and MRI of ADSCs by labeling…

Nanoparticle-Based Drug DeliveryMesenchymal stem cell researchElectrospun Nanofibers in Biomedical Applications

Engineering of chitosan and collagen macromolecules using sebacic acid for clinical applications

G. Sailakshmi、Tapas Mitra、A. Gnanamani2013-04-23Progress in Biomaterials

Transformation of natural polymers to three-dimensional (3D) scaffolds for biomedical applications faces a number of challenges, viz., solubility, stability (mechanical and thermal), strength, biocompatibility, and biodegradability. Hence, intensive research on suitable agents to provide the requisite properties has b…

Bone Tissue Engineering MaterialsElectrospun Nanofibers in Biomedical ApplicationsCollagen: Extraction and Characterization

Conjugated Polyelectrolyte Materials for Promoting Progenitor Cell Growth Without Serum

Gaomai Yang、Libing Liu、Fengting Lv 等 4 位作者2013-04-23Scientific Reports

The discovery of new active biomaterials for promoting progenitor cell growth and differentiation in serum-free medium is still proving more challenging for the clinical treatments of degenerative diseases. In this work, a conjugated polyelectrolyte, polythiophene derivative (PMNT), was discovered to significantly dri…

Hydrogels: synthesis, properties, applicationsPolymer Surface Interaction StudiesDendrimers and Hyperbranched Polymers

Decorating Metal Oxide Surfaces with Fluorescent Chlorosulfonated Corroles

Carl M. Blumenfeld、Robert H. Grubbs、Rex Moats 等 5 位作者2013-04-23Inorganic Chemistry

We have prepared 2,17-bis(chlorosulfonyl)-5,10,15-tris(pentafluorophenyl)corrole (1), 2,17-bis(chlorosulfonyl)-5,10,15-tris(pentafluorophenyl)corrolatoaluminum(III) (1-Al), and 2,17-bis(chlorosulfonyl)-5,10,15-tris(pentafluorophenyl)corrolatogallium(III) (1-Ga). The metal complexes 1-Al and 1-Ga were isolated and char…

Porphyrin and Phthalocyanine ChemistryPhotodynamic Therapy Research StudiesAnalytical Chemistry and Sensors

Strong magnetoresistance of disordered graphene

P. S. Alekseev、А. П. Дмитриев、I. V. Gornyi 等 4 位作者2013-04-23Physical Review B

We study theoretically magnetoresistance (MR) of graphene with different types of disorder. For short-range disorder, the key parameter determining magnetotransport properties---a product of the cyclotron frequency and scattering time---depends in graphene not only on magnetic field $H$ but also on the electron energy…

Graphene research and applicationsQuantum and electron transport phenomenaTopological Materials and Phenomena

Chirality Screening and Metastable States in Chiral Nematic Colloids

V. S. R. Jampani、Miha Škarabot、Simon Čopar 等 5 位作者2013-04-23Physical Review Letters

We show that forces between two colloidal particles in a thin layer of a chiral nematic liquid crystal strongly depend on the chirality of the liquid crystal. The observed pair potentials are attractive, but are oscillatory functions of colloidal separation. The number and the position of local energy minima increase…

Liquid Crystal Research AdvancementsNonlinear Dynamics and Pattern FormationMolecular spectroscopy and chirality

Innovation in Nanomedicine through Materials Nanoarchitectonics

Piotr Kujawa、Françoise M. Winnik2013-04-23Langmuir

Materials nanoarchitectonics has led to important innovations in the design and construction of systems in nanoelectronics, nanomachinery, and energy conversion. Recent publications point to the fact that the same approach may be applied successfully to other fields. In this Perspective, we define the key features of…

Nanoparticle-Based Drug DeliveryGold and Silver Nanoparticles Synthesis and ApplicationsGraphene and Nanomaterials Applications

Microstructure and A nisotropic P roperties of T extured Z r B 2 and Z r B 2 – M o S i 2 C eramics P repared by S trong M agnetic F ield A lignment

Wenwen Wu、Yoshio Sakka、T. Suzuki 等 4 位作者2013-04-23International Journal of Applied Ceramic Technology

Dense, highly textured Z r B 2 and Z r B 2 – M o S i 2 ceramics were fabricated via a strong magnetic field alignment method followed by spark plasma sintering. Unlike with the previous studies, which only focused on the alignment of single‐phase particles, both Z r B 2 and M o S i 2 , which exhibited a magnetic aniso…

Advanced ceramic materials synthesisHigh-pressure geophysics and materialsAdvanced materials and composites

Formation of Functionalized Nanowires by Control of Self‐Assembly Using Multiple Modified Amyloid Peptides

Hiroki Sakai、Ken Watanabe、Yuya Asanomi 等 11 位作者2013-04-23Advanced Functional Materials

Abstract Amyloid peptides have great potential as building blocks in the creation of functional nanowires due to their natural ability to self‐assemble into nanofibrillar structures and because they can be easily modified with various functional groups. However, significant modifications of an amyloid peptide generall…

Lipid Membrane Structure and BehaviorSupramolecular Self-Assembly in MaterialsPolydiacetylene-based materials and applications

Robust spin crossover platforms with synchronized spin switch and polymer phase transition

Fernando Novio、Emi Evangelio、Nuria Vázquez‐Mera 等 8 位作者2013-04-23Scientific Reports

The idea of developing magnetic molecular materials into real functional electronic devices with low-cost and scalable techniques appeared with the emergence of the field several years ago. Today, even though great advances have been done with this aim, the promise of a functional device working at the micro-/nanoscal…

Magnetism in coordination complexesMolecular Junctions and NanostructuresLanthanide and Transition Metal Complexes

Synergistic activity of carbosilane dendrimers in combination with maraviroc against HIV in vitro

Enrique Vacas Córdoba、Eduardo Arnáiz、F. Javier de la Mata 等 7 位作者2013-04-23AIDS

OBJECTIVE: Dendrimers have been shown as effective and safe anti-HIV compounds with great potential as topical microbicides. Currently, the most advanced microbicides are based on antiretrovirals. However, nowadays none of them has shown any success in clinical trials. DESIGN: Antiviral activity and combinatorial prof…

RNA Interference and Gene DeliveryDendrimers and Hyperbranched PolymersAntimicrobial agents and applications

Impact of Water on the Cis–Trans Photoisomerization of Hydroxychalcones

Yoann Leydet、Pınar Batat、Gediminas Jonušauskas 等 8 位作者2013-04-23The Journal of Physical Chemistry A

The photochromism of a 2-hydroxychalcone has been studied in CH3CN and H2O/CH3OH (1/1, v/v), as well as in analogous deuterated solvents using steady-state (UV-vis absorption, (1)H and (13)C NMR) and time-resolved (ultrafast transient absorption and nanosecond flow flash photolysis) spectroscopies. Whereas the irradia…

Radical Photochemical ReactionsPhotochemistry and Electron Transfer StudiesPhotochromic and Fluorescence Chemistry

Silica-coated dimers of silver nanospheres as surface-enhanced Raman scattering tags for imaging cancer cells

Xiaohu Xia、Weiyang Li、Yu Zhang 等 4 位作者2013-04-23Interface Focus

Surface-enhanced Raman scattering (SERS) tags have been actively explored as a multiplexing platform for sensitive detection of biomolecules. Here, we report a new type of SERS tags that was fabricated by sequentially functionalizing dimers made of 50 nm Ag nanospheres with 4-mercaptobenzoic acid as the Raman reporter…

Gold and Silver Nanoparticles Synthesis and ApplicationsAdvanced biosensing and bioanalysis techniquesBiosensors and Analytical Detection

Thermomechanical and shape-memory properties of epoxy-based shape-memory polymer using diglycidyl ether of ethoxylated bisphenol-A

Mengjin Fan、Heng Yu、Xiangyuan Li 等 5 位作者2013-04-23Smart Materials and Structures

A series of epoxy-based shape-memory polymers (SMPs) was prepared by using diglycidyl ether of ethoxylated bisphenol-A containing two oxyethylene units and the curing agents iso-phorone diamine and Jeffamine D230. The thermal properties, dynamic mechanical properties, mechanical properties and shape-memory properties…

Polymer composites and self-healingMarine Sponges and Natural ProductsPhotochromic and Fluorescence Chemistry

Influences of Electric-Field Distribution Along the String on the Aging of Composite Insulators

Youping Tu、Hui Zhang、Zhuo Xu 等 5 位作者2013-04-23IEEE Transactions on Power Delivery

This paper studies the uneven aging of the composite insulators along the string caused by the nonuniform electric-field distribution. Sheds along the string of two 110-kV composite insulators with varied operation time on transmission lines are analyzed systematically by means of hydrophobicity and thermally stimulat…

High voltage insulation and dielectric phenomenaPower Transformer Diagnostics and InsulationAerosol Filtration and Electrostatic Precipitation

Effects of Salt on the Gelation Mechanism of a d-Sorbitol-Based Hydrogelator

Jingjing Li、Kaiqi Fan、Libo Niu 等 5 位作者2013-04-23The Journal of Physical Chemistry B

The effect of salt on the gelatinization of 2,4-(3,4-dichlorobenzylidene)-D-sorbitol (DCBS), a novel low-molecular-weight gelator, was studied. DCBS showed pronounced hydrogelation and the electron micrographs indicated that the hydrogels consists of globular aggregates. Addition of NaCl to the aqueous medium accelera…

Lipid Membrane Structure and BehaviorSupramolecular Self-Assembly in MaterialsPhotochromic and Fluorescence Chemistry