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Thermally sensitive micelles self-assembled from poly( N -isopropylacrylamide- co - N,N -dimethylacrylamide)- b -poly( d , l -lactide- co -glycolide) for controlled delivery of paclitaxel

S. Q. Liu、Yen Wah Tong、Yi‐Yan Yang2005-06-02Molecular BioSystems

Thermally sensitive micelles self-assembled from poly(N-isopropylacrylamide-co- N,N-dimethylacrylamide)-b-poly(d,l-lactide-co-glycolide)[P(NIPAAm-co-DMAAm)-b-PLGA] are fabricated and used as a carrier for the controlled delivery of paclitaxel. Paclitaxel is efficiently loaded into the micelles by a membrane dialysis m…

Nanoparticle-Based Drug DeliveryHydrogels: synthesis, properties, applicationsAdvanced Polymer Synthesis and Characterization

Spontaneous Spreading of Nematic Liquid Crystals

Christophe Poulard、A. M. Cazabat2005-06-02Langmuir

The spontaneous spreading of macroscopic drops of nematic liquid crystals on hydrophilic substrates has been investigated by interferometric techniques. There is a complex interplay between the elastic energy, due to antagonist anchoring at the interfaces, and the radial flow in the spreading drop. A relevant paramete…

Liquid Crystal Research AdvancementsSurfactants and Colloidal SystemsElectrowetting and Microfluidic Technologies

Covalent modification of actin by 4‐hydroxy‐trans‐2‐nonenal (HNE): LC‐ESI‐MS/MS evidence for Cys374 Michael adduction

Giancarlo Aldini、Isabella Dalle‐Donne、Giulio Vistoli 等 5 位作者2005-06-02Journal of Mass Spectrometry

We demonstrate for the first time, by a combined mass spectrometric and computational approach, that G- and F-actin can be covalently modified by the lipid-derived aldehyde, 4-hydroxy-trans-2-nonenal, providing information on the molecular mass of modified protein and the mechanism and site of adduction.ESI-MS analysi…

Advanced Polymer Synthesis and Characterizationbiodegradable polymer synthesis and propertiesMass Spectrometry Techniques and Applications

Carbon-Bridged Bis(phenolato)lanthanide Alkoxides: Syntheses, Structures, and Their Application in the Controlled Polymerization of ε-Caprolactone

Yingming Yao、Xiaoping Xu、Bao Liu 等 6 位作者2005-06-02Inorganic Chemistry

A convenient method for the synthesis of lanthanide alkoxo complexes supported by a carbon-bridged bis(phenolate) ligand 2,2'-methylenebis(6-tert-butyl-4-methylphenoxo) (MBMP2-) is described. The reaction of (C5H5)3Nd with MBMPH2 in a 1:1 molar ratio in THF gave the bis(phenolato)lanthanide complex (C5H5)Nd(MBMP)(THF)…

Organometallic Complex Synthesis and Catalysisbiodegradable polymer synthesis and propertiesCarbon dioxide utilization in catalysis

Spontaneous Loading of Positively Charged Macromolecules into Alginate-Templated Polyelectrolyte Multilayer Microcapsules

Huiguang Zhu、Rohit Srivastava、Michael J. McShane2005-06-02Biomacromolecules

A simple and high-efficiency approach to loading macromolecules into microscale carriers is presented. Calcium-cross-linked alginate hydrogel microspheres were fabricated by an emulsification technique and then used as negatively charged templates to form polyelectrolyte multilayer coatings. A calcium ion chelator, ED…

Microfluidic and Capillary Electrophoresis ApplicationsPolymer Surface Interaction StudiesAdvanced Drug Delivery Systems

Predictive control of crystal size distribution in protein crystallization

Dan Shi、Prashant Mhaskar、Nael H. El‐Farra 等 4 位作者2005-06-02Nanotechnology

This work focuses on the modelling, simulation and control of a batch protein crystallization process that is used to produce the crystals of tetragonal hen egg-white (HEW) lysozyme. First, a model is presented that describes the formation of protein crystals via nucleation and growth. Existing experimental data are u…

Enzyme Structure and FunctionCrystallization and Solubility StudiesChromatography in Natural Products

Cutting single-walled carbon nanotubes

Kirk J. Ziegler、Zhenning Gu、Jonah Shaver 等 9 位作者2005-06-02Nanotechnology

A two-step process is utilized for cutting single-walled carbon nanotubes (SWNTs). The first step requires the breakage of carbon-carbon bonds in the lattice while the second step is aimed at etching at these damage sites to create short, cut nanotubes. To achieve monodisperse lengths from any cutting strategy require…

Carbon Nanotubes in CompositesGraphene research and applicationsNanotechnology research and applications

Rheological behaviour and mechanical characterization of injectable poly(propylene fumarate)/single-walled carbon nanotube composites for bone tissue engineering

Xinfeng Shi、Jared L. Hudson、Patrick P. Spicer 等 6 位作者2005-06-02Nanotechnology

This work investigated the effects of the use of a surfactant or the functionalization of single-walled carbon nanotubes (SWNTs) on their dispersion in uncrosslinked poly(propylene fumarate) (PPF) and the mechanical reinforcement of crosslinked composites as a function of the SWNT concentration. Rheological measuremen…

Carbon Nanotubes in CompositesPolymer Nanocomposites and PropertiesOrthopaedic implants and arthroplasty

Model for Reversible Colloidal Gelation

Emanuela Zaccarelli、Sergey V. Buldyrev、Emilia La Nave 等 7 位作者2005-06-02Physical Review Letters

We report a numerical study, covering a wide range of packing fraction Phi and temperature T, for a system of particles interacting via a square well potential supplemented by an additional constraint on the maximum number n(max) of bonded interactions. We show that, when n(max)<6, the liquid-gas coexistence region sh…

Material Dynamics and PropertiesTheoretical and Computational PhysicsAdvanced Thermodynamics and Statistical Mechanics

Model Based Analysis and Control Design of a Urea-SCR deNOx Aftertreatment System

Devesh Upadhyay、Michiel Van Nieuwstadt2005-06-02Journal of Dynamic Systems Measurement and Control

In this paper we tackle issues relevant to model based control design for a Urea based Selective Catalytic Reduction (SCR) process relevant to automotive applications. A three state, control oriented, lumped parameter model of the system is used to investigate essential controllability and observability properties of…

Catalytic Processes in Materials ScienceFuel Cells and Related MaterialsAdvanced Control Systems Optimization

Nanostructured Ceramic Oxides with a Slow Crack Growth Resistance Close to Covalent Materials

J. Chevalier、S. Deville、G. Fantozzi 等 8 位作者2005-06-02Nano Letters

Oxide ceramics are sensitive to slow crack growth because adsorption of water can take place at the crack tip, leading to a strong decrease of the surface energy in humid (or air) conditions. This is a major drawback concerning demanding, long-term applications such as orthopaedic implants. Here we show that a specifi…

Ferroelectric and Piezoelectric MaterialsAdvanced ceramic materials synthesisNuclear materials and radiation effects

STM Single Atom/Molecule Manipulation and Its Application to Nanoscience and Technology

Saw-Wai Hla2005-06-02arXiv

Single atom/molecule manipulation with a scanning-tunneling-microscope (STM) tip is an innovative experimental technique of nanoscience. Using STM-tip as an engineering or analytical tool, artificial atomic-scale structures can be fabricated, novel quantum phenomena can be probed, and properties of single atoms and mo…

Materials Science

On the melting of the nanocrystalline vortex matter in high-temperature superconductors

Yadin Y. Goldschmidt、Eduardo Cuansing2005-06-02arXiv

Multilevel Monte Carlo simulations of the vortex matter in the highly-anisotropic high-temperature superconductor Bi$_2$Sr$_2$CaCu$_2$O$_8$ were performed. We introduced low concentration of columnar defects satisfying $B_ϕ\le B$. Both the electromagnetic and Josephson interactions among pancake vortices were included…

Materials Sciencecond-mat.stat-mechSuperconductivity

Exciton Dissociation Dynamics in Model Donor-Acceptor Polymer Heterojunctions: I. Energetics and Spectra

Eric R. Bittner、John Glenn Santos Ramon、Stoyan Karabunarliev2005-06-02arXiv

In this paper we consider the essential electronic excited states in parallel chains of semiconducting polymers that are currently being explored for photovoltaic and light-emitting diode applications. In particular, we focus upon various type II donor-acceptor heterojunctions and explore the relation between the exci…

Materials Science

Coordinate scaling in time-dependent current density functional theory

Maxime Dion、Kieron Burke2005-06-02arXiv

The coupling constant dependence is derived in time-dependent {\em current} density functional theory. The scaling relation can be used to check approximate functionals and in conjunction with the adiabatic connection formula to obtain the ground-state energy from the exchange-correlation kernel. The result for the un…

Materials ScienceChemical Physics

How the Liquid-Liquid Transition Affects Hydrophobic Hydration in Deeply Supercooled Water

Dietmar Paschek2005-06-02Physical Review Letters

We determine the phase diagram of liquid supercooled water by extensive computer simulations using the TIP5P-E model. We find that the transformation of water into a low density liquid in the supercooled range strongly enhances the solubility of hydrophobic particles. The transformation of water into a tetrahedrally s…

Phase Equilibria and ThermodynamicsMaterial Dynamics and PropertiesTheoretical and Computational Physics

From Random Walk to Single-File Diffusion

Binhua Lin、Mati Meron、Bianxiao Cui 等 5 位作者2005-06-02Physical Review Letters

We report an experimental study of diffusion in a quasi-one-dimensional (q1D) colloid suspension which behaves like a Tonks gas. The mean squared displacement as a function of time is described well with an ansatz encompassing a time regime that is both shorter and longer than the mean time between collisions. The ans…

Material Dynamics and PropertiesTheoretical and Computational PhysicsStochastic processes and statistical mechanics

Quantum Nernst Effect

HIROAKI NAKAMURA、Naomichi Hatano、Ryoen Shirasaki2005-06-02arXiv

It is theoretically predicted that the Nernst coefficient is strongly suppressed and the thermal conductance is quantized in the quantum Hall regime of the two-dimensional electron gas. The Nernst effect is the induction of a thermomagnetic electromotive force in the $y$ direction under a temperature bias in the $x$ d…

Mesoscale and Nanoscale PhysicsMaterials Science

Relation between driving energy, crack shape and speed in brittle dynamic fracture

Andrea Parisi、Robin C. Ball2005-06-02arXiv

We report results on the interrelation between driving force, roughness exponent, branching and crack speed in a finite element model. We show that for low applied loadings the crack speed reaches the values measured in the experiments, and the crack surface roughness is compatible with logarithmic scaling. At higher…

Materials Sciencecond-mat.stat-mech

Soft Plasma Treated Surfaces: Tailoring of Structure and Properties for Biomaterial Applications

Renate Förch、Zhihong Zhang、Wolfgang Knoll2005-06-02Plasma Processes and Polymers

Abstract Summary: This paper aims to discuss and review developments in plasma surface modification techniques which have been seen over the past few years, with particular emphasis on low energy or soft plasma assisted surface polymerisation processes. While early work focussed mainly on protective coatings and surfa…

Surface Modification and SuperhydrophobicityPolymer Surface Interaction StudiesNanofabrication and Lithography Techniques