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Porphyrins and Phthalocyanines Decorated with Dendrimers: Synthesis and Biomedical Applications

Flávio Figueira、Patrícia M. R. Pereira、Sandrina Silva 等 5 位作者2014-02-01Current Organic Synthesis

In medical applications such as drug delivery, gene transfection and imaging the formation of systems with well-defined sizes and shapes are of significant interest. For this reason the design of dendrimers with modulated size, shape, branching length/density, and their surface functionality, clearly distinguishes the…

Porphyrin and Phthalocyanine ChemistryPhotodynamic Therapy Research Studies

Enrichment of breast cancer stem-like cells by growth on electrospun polycaprolactone-chitosan nanofiber scaffolds

Jennifer Sims‐Mourtada、Rohina A. Niamat、Shani Samuel 等 5 位作者2014-02-01International Journal of Nanomedicine

A small population of highly tumorigenic breast cancer cells has recently been identified. These cells, known as breast-cancer stem-like cells (BCSC), express markers similar to mammary stem cells, and are highly resistant to chemotherapy. Currently, study of BCSC is hampered by the inability to propagate these cells…

Mesenchymal stem cell researchCancer Cells and MetastasisElectrospun Nanofibers in Biomedical Applications

Assembly of a Bacteriophage-Based Template for the Organization of Materials into Nanoporous Networks

Hammond, Paula T.、Dorval Courchesne, Noemie-Manuelle、Matthew T. Klug 等 10 位作者2014-02-01DSpace@MIT (Massachusetts Institute of Technology)

M13 bacteriophages are assembled via a covalent layer-by-layer process to form a highly nanoporous network capable of organizing nanoparticles and acting as a scaffold for templating metal-oxides. The morphological and optical properties of the film itself are presented as well as its ability to organize and disperse…

Advanced biosensing and bioanalysis techniquesQuantum Dots Synthesis And PropertiesAnodic Oxide Films and Nanostructures

Imaging and analysis techniques for electrical trees using X-ray computed tomography

Roger Schurch、Simon Rowland、Robert S. Bradley 等 4 位作者2014-02-01IEEE Transactions on Dielectrics and Electrical Insulation

Electrical treeing is one of the main mechanisms of degradation in polymeric high voltage insulation, a precursor of power equipment failure. Electrical trees have been previously imaged mostly using two-dimensional imaging techniques; thereby loosing valuable information. Here we review the techniques that have been…

High voltage insulation and dielectric phenomenaPower Transformer Diagnostics and InsulationElectrostatic Discharge in Electronics

The influence of biodegradable magnesium alloys on the osteogenic differentiation of human mesenchymal stem cells

Rachel Li、Nicholas Travis Kirkland、John Truong 等 7 位作者2014-02-01Journal of Biomedical Materials Research Part A

The postdegradation effect of pure Mg, Mg-1Y, Mg-5Al, and Mg-2Ca alloys on the differentiation, proliferation and gene expression of human mesenchymal stem cells (hMSCs) was investigated. It was revealed that that Mg(2+) ions result in an increase in cell proliferation. However, we observed a maximum concentration (ap…

Magnesium Alloys: Properties and ApplicationsAluminum Alloys Composites PropertiesHydrogen Storage and Materials

Finite-Element Modeling of Magnetic Material Degradation Due to Punching

Madeleine Bali、Herbert De Gersem、Annette Muetze2014-02-01IEEE Transactions on Magnetics

Aiming to better understand and model the different loss mechanisms occurring within electric machines during operation, we present a method to consider the degradation of steel during manufacturing due to punching in finite-element modeling of electric machines. The approach introduces a certain number of boundary la…

Electric Motor Design and AnalysisMagnetic Properties and ApplicationsNon-Destructive Testing Techniques

Iron Losses in a Medium-Frequency Transformer Operated in a High-Power DC–DC Converter

Nils Soltau、Daniel Eggers、Kay Hameyer 等 4 位作者2014-02-01IEEE Transactions on Magnetics

The three-phase dual-active bridge is a dc–dc converter, which is highly suitable for high-power applications. Among others, this is due to the medium-frequency transformer in the ac link, which provides galvanic isolation. The transformer is operated with a square-shaped voltage waveform. The flux density in the tran…

Advanced DC-DC ConvertersSilicon Carbide Semiconductor TechnologiesMagnetic Properties and Applications

Toxicity of quantum dots on respiratory system

Tianshu Wu、Meng Tang2014-02-01Inhalation Toxicology

Quantum dots (QDs), as advanced nanotechnology products, are widely used in the bio-medical field for diagnostic and therapeutic purposes due to their unique properties. Therefore, it becomes important for researchers to elucidate the adverse effects of QDs on human beings. This essay provides an overview of the toxic…

Advanced biosensing and bioanalysis techniquesQuantum Dots Synthesis And PropertiesCarbon and Quantum Dots Applications

Production of polyhydroxyalkanoates (PHAs) by Bacillus subtilis and Escherichia coli grown on cane molasses fortified with ethanol

Eman Zakaria Gomaa2014-02-01Brazilian Archives of Biology and Technology

The aim of this work was to study the production of polyhydroxyalkanoates (PHAs) by Bacillus subtilis and Escherichia coli isolated from the industrial contaminated soil samples using cane molasses as an inexpensive substrate. The amount of PHA accumulated followed a similar pattern to its growth for each of treatment…

biodegradable polymer synthesis and propertiesMicroplastics and Plastic PollutionGraphene and Nanomaterials Applications

GE11-modified liposomes for non-small cell lung cancer targeting: preparation, ex vitro and in vivo evaluation

Dawei Chen、Liang Cheng、Fazhen Huang 等 8 位作者2014-02-01International Journal of Nanomedicine

Non-small cell lung cancer (NSCLC) is a serious threat to human health, and 40%-80% of NSCLCs express high levels of epidermal growth factor receptor (EGFR). GE11 is a novel peptide and exhibits high affinity for EGFR binding. The aim of this study was to construct and evaluate GE11-modified liposomes for targeted dru…

Nanoparticle-Based Drug DeliveryRNA Interference and Gene DeliveryCancer Research and Treatments

Modelling and predicting the biological effects of nanomaterials

David A. Winkler、Frank R. Burden、Bing Yan 等 7 位作者2014-02-01SAR and QSAR in environmental research

The commercial applications of nanoparticles are growing rapidly, but we know relatively little about how nanoparticles interact with biological systems. Their value--but also their risk--is related to their nanophase properties being markedly different to those of the same material in bulk. Experiments to determine h…

Nanoparticles: synthesis and applications

General Aspects of Yield Stress Fluids – Terminology and Definition of Viscosity

Boisly Martin、Kästner Markus、Brummund Jörg 等 4 位作者2014-02-01Applied Rheology

This work contributes to general theoretical aspects of yield stress fluids with significance for practical phenomenological material modeling. It introduces a terminology so that the material class ‘yield stress fluid’ is defined and can be distinguished from the terms ‘solid’ and ‘liquid’. This new material classifi…

Structural and Thermomechanical Investigation of Lyotropic Liquid Crystal Phases Doped with Monodisperse Microparticles

Ponton A.、Meyer C.、Foyart G. 等 5 位作者2014-02-01Applied Rheology

We present a study of the structural and thermomechanical properties of lyotropic phase in the quasi ternary system made of Cetylpyridinium chloride (CPCl)/hexanol/salt water (0.9 % by mass) with and without cobalt microparticles. Phase transition temperatures of the structural sequence isotropic L 1/nematic calamitic…

Energetic and Peak Power Advantages of Series Elastic Actuators in an Actuated Prosthetic Leg for Walking and Running

Martin Grimmer、Mahdy Eslamy、André Seyfarth2014-02-01Actuators

A monoarticular series elastic actuator (SEA) reduces energetic and peak power requirements compared to a direct drive (DD) in active prosthetic ankle-foot design. Simulation studies have shown that similar advantages are possible for the knee joint. The aims of this paper were to investigate the advantages of a monoa…

Electric-field-induced phase transitions in co-doped Pb(Zr1−xTix)O3at the morphotropic phase boundary

D. J. Franzbach、Yohan Seo、Andrew J. Studer 等 10 位作者2014-02-01Science and Technology of Advanced Materials

⩽ 0.60. The investigated compositions were located in the vicinity of the morphotropic phase boundary, giving insight into the influence of crystal structure on the hysteretic ferroelectric behavior. The remanent strain of particular compositions is shown to be larger than theoretically allowed by ferroelectric switch…

Ferroelectric and Piezoelectric MaterialsMultiferroics and related materialsMicrowave Dielectric Ceramics Synthesis

On the Use of an Internal Mixer to Study the Impregnation of Carbon Fillers by Organic Liquids

Carrot Christian、Akkoyun Meral、Blottière Benoît2014-02-01Applied Rheology

Impregnation of organic liquid electrolytes in conductive powders is of major importance in the field of energy storage devices such as batteries or super-capacitors. Impregnation during mixing and processing operations becomes usual for practical reasons and requires a better understanding of the changes of the rheol…

Atomic force microscopy visualization of hard segment alignment in stretched polyurethane nanofibers prepared by electrospinning

Hiroaki Sakamoto、Hitoshi Asakawa、Takeshi Fukuma 等 5 位作者2014-02-01Science and Technology of Advanced Materials

Molecular-level orientation within nanofibers has been attracting attention as a tool for controlling and designing highly functional nanofibers. In this study, we used atomic force microscopy to visualize the phase separation between soft and hard segments on a polyurethane (PU) nanofiber surface prepared by electros…

Advanced Sensor and Energy Harvesting MaterialsElectrospun Nanofibers in Biomedical ApplicationsPolymer composites and self-healing

Activation of Al–Cu–Fe quasicrystalline surface: fabrication of a fine nanocomposite layer with high catalytic performance

Satoshi Kameoka、Toyokazu Tanabe、F. Satoh 等 5 位作者2014-02-01Science and Technology of Advanced Materials

A fine layered nanocomposite with a total thickness of about 200 nm was formed on the surface of an Al63Cu25Fe12 quasicrystal (QC). The nanocomposite was found to exhibit high catalytic performance for steam reforming of methanol. The nanocomposite was formed by a self-assembly process, by leaching the Al–Cu–Fe QC usi…

Quasicrystal Structures and PropertiesNanocluster Synthesis and ApplicationsMineralogy and Gemology Studies

Characterization of Material Viscoelasticity at Large Deformations

Malkin Alexander、Ilyin Sergey、Kulichikhin Valery2014-02-01Applied Rheology

Mechanical properties of various technological materials at large deformations are proposed to characterize by means of some generalized parameters obtained at large oscillation strains but not related to any definite rheological equations. The base for the analysis is the Lissajous-Bowditch figures in two coordinate…