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Controlled delivery of drugs through smart pH-sensitive nanohydrogels for anti-cancer therapies: synthesis, drug release and cellular studies

A. Álvarez-Bautista、Catarina M.M. Duarte、E. Mendizábal 等 4 位作者2016-03-03Designed Monomers & Polymers

Nanohydrogels were synthesized by microemulsion polymerization. These nanohydrogels were pre-designed to be pH and temperature stimuli-response materials, using N-isopropylacrilamide as a base monomer and 1-vinyl imidazole as ionizable comonomer. The pH sensitivity was confirmed by measuring the increase or decrease i…

Nanoparticle-Based Drug DeliveryHydrogels: synthesis, properties, applicationsAdvanced Polymer Synthesis and Characterization

Some Cavitation Properties of Liquids

К. Д. Ефремова、V. N. Pilgunov2016-03-03Science and Education of the Bauman MSTU

Cavitation properties of liquid must be taken into consideration in the engineering design of hydraulic machines and hydro devices when there is a possibility that in their operation an absolute pressure in the liquid drops below atmospheric one, and for a certain time the liquid is in depression state. Cold boiling,…

Material Properties and ApplicationsCoal Combustion and Slurry ProcessingEngineering Diagnostics and Reliability

Orbital effects of strong magnetic field on a two-dimensional Holstein polaron

Subhasree Pradhan、Monodeep Chakraborty、A. Taraphder2016-03-03Physical review. B./Physical review. B

We investigate the orbital effects of a strong external magnetic field on the ground-state properties of a two-dimensional (2D) Holstein polaron, employing variational approaches based on exact diagonalization. From the ground-state energy and the wave function, we calculate the electron-phonon correlation function, t…

Physics of Superconductivity and MagnetismQuantum and electron transport phenomenaMagnetic and transport properties of perovskites and related materials

Modular synthesis of functional polymer nanoparticles from a versatile platform based on poly(pentafluorophenylmethacrylate)

Yeon‐Ju Lee、Jeffrey Pyun、Jeewoo Lim 等 4 位作者2016-03-03Journal of Polymer Science Part A Polymer Chemistry

Control of functionalities in polymer nanoparticles (PNPs) is important for their application. Thus, there is an interest for well-defined nanoparticle platforms to which desired functions could readily, and in modular fashion, be imparted. Herein, we report an amine-reactive PNP platform for the modular synthesis of…

Advanced Polymer Synthesis and CharacterizationPolymer Nanocomposites and PropertiesPolymer Surface Interaction Studies

Optical properties of plasmonic nanopillars in extended quasi-static limits

Atefe Fazel Najafabadi、Tavakol Pakizeh2016-03-03Journal of the Optical Society of America B

An extended method based on the long-wavelength approximations is introduced to investigate the optical properties of finite-size metal nanopillars for different incident light polarizations. In this proposed method, the optical depolarization factors are the key parameters and strongly depend on the position of the c…

Gold and Silver Nanoparticles Synthesis and ApplicationsMetamaterials and Metasurfaces ApplicationsPlasmonic and Surface Plasmon Research

Design and optimization of photolithography friendly photonic components

James Pond、Xu Wang、Jonas Flueckiger 等 7 位作者2016-03-03Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

Silicon photonics is a scalable, cost-effective technology for the production of photonic integrated circuits (PICs). The emergence of silicon photonics as a dominant technology for PICs is largely because it leverages decades of investment in design and fabrication technologies for electronic integrated circuits. How…

Advanced Fiber Optic SensorsPhotonic and Optical DevicesOptical Coatings and Gratings

Site preferences and effects of X (X = Mn, Fe, Co, Cu) on the properties of NiAl: A first-principles study

Hongshan Li、Yong Cao、Shenggang Zhou 等 5 位作者2016-03-03Modern Physics Letters B

The site preference of X (X = Mn, Fe, Co, Cu) in NiAl and its effects on structural, electronic and elastic properties were investigated by performing first-principles calculations using density functional theory (DFT). Formation enthalpy calculations show that adding X increases the formation enthalpy of NiAl, indica…

Hydrogen Storage and MaterialsIntermetallics and Advanced Alloy PropertiesMXene and MAX Phase Materials

o-Quinones Derived from Tribenzotriquinacenes: Functionalization of Inner Bay Positions and Use for Single-Wing Extensions

Yufei Zhang、Wan‐Fa Tian、Xiao‐Ping Cao 等 5 位作者2016-03-03The Journal of Organic Chemistry

Through a surprisingly nonregioselective oxidation process, the reaction of two analogous 2-hydroxy-substituted tribenzotriquinacenes (TBTQs) 8a/8b by o-iodoxybenzoic acid was found to afford the corresponding Cs- and C1-symmetrical TBTQ-o-quinones 6a/6b and 7a/7b, respectively, in 1:1 ratio and excellent combined yie…

Porphyrin and Phthalocyanine ChemistryCancer Treatment and PharmacologyOxidative Organic Chemistry Reactions

Oscillation control of carbon nanotube mechanical resonator by electrostatic interaction induced retardation

Masaaki Yasuda、Kuniharu Takei、Takayuki Arie 等 4 位作者2016-03-03Scientific Reports

Despite the superb intrinsic properties of carbon nanotube mechanical resonators, the quality factors at room temperature are 1,000 or less, even in vacuum, which is much lower than that of mechanical resonators fabricated using a top-down approach. This study demonstrates the improvement of the quality factor and the…

Carbon Nanotubes in CompositesForce Microscopy Techniques and ApplicationsMechanical and Optical Resonators

Structure and Properties of Ir-Containing Oxides with Large Spin–Orbit Coupling: Ba2In2–xIrxO5+δ

Joshua Flynn、Jun Li、A.W. Sleight 等 5 位作者2016-03-03Inorganic Chemistry

In this work, the solid solution series Ba2In(2-x)Ir(x)O5+δ (x = 0-1.4, 2) was synthesized, and its structural, magnetic, and charge-transport properties were measured. With increasing Ir content, three transitions in the room-temperature structure were observed: orthorhombic to tetragonal to cubic to a monoclinic dis…

Magnetic and transport properties of perovskites and related materialsMultiferroics and related materialsAdvanced Condensed Matter Physics

Eliminating Measurement Cable Effects From Transformer Admittance Measurements

Bjørn Gustavsen2016-03-03IEEE Transactions on Power Delivery

Admittance frequency-sweep measurements is an accepted procedure for characterizing transformer terminal behavior for the purpose of frequency-dependent black-box modeling. The errors introduced by the measurement cables is with one existing practice mitigated by removal of the associated shunt capacitance effect. In…

High voltage insulation and dielectric phenomenaLightning and Electromagnetic PhenomenaThermal Analysis in Power Transmission

Improving Functional Annotation in the DRE-TIM Metallolyase Superfamily through Identification of Active Site Fingerprints

Garima Kumar、Jordyn L. Johnson、Patrick A. Frantom2016-03-03Biochemistry

Within the DRE-TIM metallolyase superfamily, members of the Claisen-like condensation (CC-like) subgroup catalyze C-C bond-forming reactions between various α-ketoacids and acetyl-coenzyme A. These reactions are important in the metabolic pathways of many bacterial pathogens and serve as engineering scaffolds for the…

Corrosion Behavior and InhibitionGalectins and Cancer BiologyPeptidase Inhibition and Analysis

Automating impurity-enhanced antiphase boundary energy calculations from ab initio Monte Carlo

Ruoshi Sun、Axel van de Walle2016-03-03Calphad

The effect of impurities on antiphase boundary (APB) energies is studied using cluster expansion and Monte Carlo (MC) techniques from first-principles total-energy calculations. We present a code that automates the generation of APB structures for MC sampling within the Alloy Theoretic Automated Toolkit software packa…

Advanced Chemical Physics StudiesSuperconducting Materials and ApplicationsMachine Learning in Materials Science

Localizing Perturbations of the Racemic Equilibria Involving Dipicolinate‐Derived Lanthanide(III) Complexes

Brian Nguyen、A. Ingram、Gilles Muller2016-03-03Chirality

Helical D3 tris(4-amino-2,6-pyridine-dicarboxylate)terbium(III) and europium(III) complexes, which form a racemic equilibrium in aqueous solution, were prepared to study their secondary coordination sphere interactions with chiral amino acids. These interactions were probed using a combination of circularly polarized…

Molecular Sensors and Ion DetectionLanthanide and Transition Metal ComplexesMolecular spectroscopy and chirality

Thermoelastic interactions without energy dissipation in an unbounded body with a cylindrical cavity

Hany H. Sherief、W. E. Raslan2016-03-03Journal of Thermal Stresses

In this work, we apply Green and Naghdi's generalized thermoelasticity theory to a one-dimensional problem of an infinitely long cylindrical cavity. Laplace transform techniques are used to solve the problem. A comparison of generalized thermoelasticity theory with one relaxation time is made. Numerical results are co…

Thermoelastic and Magnetoelastic PhenomenaNonlocal and gradient elasticity in micro/nano structuresElasticity and Wave Propagation

Photothermal lesions in soft tissue induced by optical fiber microheaters

Reinher Pimentel‐Domínguez、Paola Moreno‐Alvarez、Mathieu Hautefeuille 等 5 位作者2016-03-03Biomedical Optics Express

Photothermal therapy has shown to be a promising technique for local treatment of tumors. However, the main challenge for this technique is the availability of localized heat sources to minimize thermal damage in the surrounding healthy tissue. In this work, we demonstrate the use of optical fiber microheaters for ind…

Gold and Silver Nanoparticles Synthesis and ApplicationsNanoplatforms for cancer theranosticsPhotoacoustic and Ultrasonic Imaging

Self-Assembly of Reactive Linear Cu3 Building Blocks for Supramolecular Coordination Chemistry and Their Reactivity toward En Ligand Complexes

M. Fleischmann、Luis Dütsch、Mehdi Elsayed Moussa 等 7 位作者2016-03-03Inorganic Chemistry

This study describes the selective synthesis of linear, trinuclear, halide-bridged Cu(I) complexes [Cu3(μ-X)2(μ-dpmp)2(MeCN)2](+) (1a: X = Cl; 1b: X = Br; 1c: X = I) stabilized by the tridentate dpmp ligand obtained by self-assembly reactions in THF/MeCN. Upon drying, the MeCN ligands can be removed and the complexes…

Metal-Organic Frameworks: Synthesis and ApplicationsMetal complexes synthesis and propertiesMagnetism in coordination complexes

Study of the effective parameters on stress distribution around triangular hole in metallic plates subjected to uniform heat flux

Mohammad Jafari、Mohammad Bagher Nazari、Amir Taheri Nasab2016-03-03Journal of Thermal Stresses

On the basis of the steady-state two-dimensional theory of thermoelasticity, stress field around a triangular hole in an infinite isotropic plate is discussed. A metallic plate subjected to uniform heat flux and thermal-insulated condition along the hole boundary is assumed. The method used for this study is the expan…

Numerical methods in engineeringThermal Analysis in Power TransmissionMaterial Properties and Failure Mechanisms

BBB-Permeable, Neuroprotective, and Neurotrophic Polysaccharide, Midi-GAGR

Vishruti Makani、Yong-gil Jang、K. Christopher 等 9 位作者2016-03-03PLoS ONE

An enormous amount of efforts have been poured to find an effective therapeutic agent for the treatment of neurodegenerative diseases including Alzheimer's disease (AD). Among those, neurotrophic peptides that regenerate neuronal structures and increase neuron survival show a promise in slowing neurodegeneration. Howe…

Hydrogels: synthesis, properties, applicationsNerve injury and regenerationbiodegradable polymer synthesis and properties

Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina

Uchenna Unachukwu、Alice Warren、Ze Li 等 9 位作者2016-03-03Scientific Reports

To replace photoreceptors lost to disease or trauma and restore vision, laboratories around the world are investigating photoreceptor replacement strategies using subretinal transplantation of photoreceptor precursor cells (PPCs) and retinal progenitor cells (RPCs). Significant obstacles to advancement of photorecepto…

Retinal Diseases and TreatmentsRetinal Development and DisordersPhotochromic and Fluorescence Chemistry