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Biomedical Imaging in Implantable Drug Delivery Systems

Haoyan Zhou、Christopher Hernandez、Monika Goss 等 5 位作者2015-07-16Current Drug Targets

Implantable drug delivery systems (DDS) provide a platform for sustained release of therapeutic agents over a period of weeks to months and sometimes years. Such strategies are typically used clinically to increase patient compliance by replacing frequent administration of drugs such as contraceptives and hormones to…

Nanoparticle-Based Drug DeliveryAdvanced MRI Techniques and ApplicationsUltrasound and Hyperthermia Applications

Transient Absorption Spectroscopy for Polymer Solar Cells

Hideo Ohkita、Yasunari Tamai、Hiroaki Benten 等 4 位作者2015-07-16IEEE Journal of Selected Topics in Quantum Electronics

Time-resolved spectroscopy is a powerful tool for studying fundamental photophysics in optoelectronic materials on a molecular temporal scale. In this review, we describe transient spectroscopic studies on fundamental photovoltaic conversion processes in polymer solar cells, which consist of a series of conversion pro…

Organic Electronics and PhotovoltaicsThin-Film Transistor TechnologiesConducting polymers and applications

Multifunctional magnetic-hollow gold nanospheres for bimodal cancer cell imaging and photothermal therapy

Ling-Yu Bai、Xiaoquan Yang、Jie An 等 12 位作者2015-07-16Nanotechnology

Multifunctional nanocomposites combining imaging and therapeutic functions have great potential for cancer diagnosis and therapy. In this work, we developed a novel theranostic agent based on hollow gold nanospheres (HGNs) and superparamagnetic iron oxide nanoparticles (SPIO). Taking advantage of the excellent magneti…

Gold and Silver Nanoparticles Synthesis and ApplicationsNanoplatforms for cancer theranosticsPhotoacoustic and Ultrasonic Imaging

Mycolactone-Dependent Depletion of Endothelial Cell Thrombomodulin Is Strongly Associated with Fibrin Deposition in Buruli Ulcer Lesions

Joy Ogbechi、Marie-Thérèse Ruf、Belinda S. Hall 等 11 位作者2015-07-16PLoS Pathogens

A well-known histopathological feature of diseased skin in Buruli ulcer (BU) is coagulative necrosis caused by the Mycobacterium ulcerans macrolide exotoxin mycolactone. Since the underlying mechanism is not known, we have investigated the effect of mycolactone on endothelial cells, focussing on the expression of surf…

Mycobacterium research and diagnosisPhytochemistry and Bioactive CompoundsInfectious Diseases and Mycology

A Three-Band Substrate Integrated Waveguide Leaky-Wave Antenna Based on Composite Right/Left-Handed Structure

Seyed Sasan Haghighi、Abbas Ali Heidari、Masoud Movahhedi2015-07-16IEEE Transactions on Antennas and Propagation

In this communication, the design and implementation of a three-band substrate integrated waveguide (SIW) leaky-wave antenna (LWA) based on the composite right/left-handed (CRLH) structure is presented. CRLH unit cell of the proposed antenna is composed of two adjacent interdigital slots with two vias between them. Tw…

Metamaterials and Metasurfaces ApplicationsMicrowave Engineering and WaveguidesAdvanced Antenna and Metasurface Technologies

Theory of Tribotronics

Ying Liu、Simiao Niu、Zhong Lin Wang2015-07-16Advanced Electronic Materials

As a potential next generation mechanical‐to‐electricity power generator, the triboelectric nanogenerator (TENG) has drawn considerable attention in recent years. Its mechanical‐to‐electrical signal control properties also gave rise to the original idea of “tribotronics”, which utilize triboelectric output to drive/co…

Advanced Sensor and Energy Harvesting MaterialsConducting polymers and applicationsMuscle activation and electromyography studies

Simultaneous control of haze and transmittance using a dye-doped cholesteric liquid crystal cell

Byeong‐Hun Yu、Jae‐Won Huh、Joon Heo 等 4 位作者2015-07-16Liquid Crystals

We propose a light shutter device using dye-doped cholesteric liquid crystals for a high-visibility see-through display. In the focal-conic state, the proposed device can perfectly block the background image through simultaneous use of light scattering and absorption effects in a single-layered structure. By switching…

Liquid Crystal Research AdvancementsPhotonic Crystals and ApplicationsAdvanced Optical Imaging Technologies

Silicate weathering in the Ganges alluvial plain

Patrick Frings、Wim Clymans、Guillaume Fontorbe 等 7 位作者2015-07-16Earth and Planetary Science Letters

The Ganges is one of the world's largest rivers and lies at the heart of a body of literature that investigates the interaction between mountain orogeny, weathering and global climate change. Three regions can be recognised in the Ganges basin, with the Himalayan orogeny to the north and the plateaus of peninsular Ind…

Geology and Paleoclimatology ResearchGeochemistry and Elemental AnalysisClay minerals and soil interactions

Hydrogen Production from Water by Photolysis, Sonolysis and Sonophotolysis with Solid Solutions of Rare Earth, Gallium and Indium Oxides as Heterogeneous Catalysts

Marta Penconi、Federico Rossi、F. Ortica 等 5 位作者2015-07-16Sustainability

In this work, we present the hydrogen production by photolysis, sonolysis and sonophotolysis of water in the presence of newly synthesized solid solutions of rare earth, gallium and indium oxides playing as catalysts. From the experiments of photolysis, we found that the best photocatalyst is the solid solution Y0.8Ga…

Advanced Photocatalysis TechniquesZnO doping and propertiesGas Sensing Nanomaterials and Sensors

Design and Optimization of SiON Ring Resonator-Based Biosensors for Aflatoxin M1 Detection

Romain Guider、Davide Gandolfi、Tatevik Chalyan 等 8 位作者2015-07-16Sensors

In this article, we designed and studied silicon oxynitride (SiON) microring-based photonic structures for biosensing applications. We designed waveguides, directional couplers, and racetrack resonators in order to measure refractive index changes smaller than 10-6 refractive index units (RIU). We tested various sampl…

Photonic and Optical DevicesSilicon Nanostructures and PhotoluminescenceMechanical and Optical Resonators

Collagen I and the fibroblast: High protein expression requires a new paradigm of post-transcriptional, feedback regulation

Richard I. Schwarz2015-07-16Biochemistry and Biophysics Reports

BACKGROUND: Scaling protein production seems like a simple perturbation of transcriptional control. However, when embryonic tendon fibroblasts have to produce >50% procollagen and secrete it from the cell 4 times faster than the average protein, this taxes the cellular machinery and requires a fresh look at how the pa…

Tendon Structure and TreatmentCollagen: Extraction and CharacterizationConnective Tissue Growth Factor Research

Improved Geometry of Decellularized Tissue Engineered Heart Valves to Prevent Leaflet Retraction

Bart Sanders、Sandra Loerakker、Emanuela S. Fioretta 等 7 位作者2015-07-16Annals of Biomedical Engineering

Recent studies on decellularized tissue engineered heart valves (DTEHVs) showed rapid host cell repopulation and increased valvular insufficiency developing over time, associated with leaflet shortening. A possible explanation for this result was found using computational simulations, which revealed radial leaflet com…

Cardiac Valve Diseases and TreatmentsElectrospun Nanofibers in Biomedical ApplicationsTissue Engineering and Regenerative Medicine

Systematic Optimization of a Force Field for Classical Simulations of TiO2?Water Interfaces

Erik G. Brandt、Alexander P. Lyubartsev2015-07-16The Journal of Physical Chemistry C

Abstract Atomistic force field parameters were developed for the TiO2?water interface by systematic optimization with respect to experimentally determined crystal structures (lattice parameters) and surface thermodynamics (water adsorption enthalpy). Optimized force field parameters were determined for the two cases w…

Polymer Surface Interaction StudiesSpectroscopy and Quantum Chemical StudiesElectrochemical Analysis and Applications

Redox‐Active Metal–Organic Frameworks: Highly Stable Charge‐Separated States through Strut/Guest‐to‐Strut Electron Transfer

Nivedita Sikdar、Kolleboyina Jayaramulu、Venkayala Kiran 等 7 位作者2015-07-16Chemistry - A European Journal

Molecular organization of donor and acceptor chromophores in self-assembled materials is of paramount interest in the field of photovoltaics or mimicry of natural light-harvesting systems. With this in mind, a redox-active porous interpenetrated metal-organic framework (MOF), {[Cd(bpdc)(bpNDI)]⋅4.5 H2 O⋅DMF}n (1) has…

Metal-Organic Frameworks: Synthesis and ApplicationsMagnetism in coordination complexesCrystallography and molecular interactions

Three-Dimensional Compound Comparison Methods and Their Application in Drug Discovery

Woong‐Hee Shin、Xiaolei Zhu、Mark G. Bures 等 4 位作者2015-07-16Molecules

Virtual screening has been widely used in the drug discovery process. Ligand-based virtual screening (LBVS) methods compare a library of compounds with a known active ligand. Two notable advantages of LBVS methods are that they do not require structural information of a target receptor and that they are faster than st…

Protein Structure and DynamicsComputational Drug Discovery MethodsMachine Learning in Materials Science

Anomalous dynamical scaling from nematic and U(1) gauge field fluctuations in two-dimensional metals

Tobias Holder、Walter Metzner2015-07-16Physical Review B

We analyze the scaling theory of two-dimensional metallic electron systems in the presence of critical bosonic fluctuations with small wave vectors, which are either due to a $\text{U}(1)$ gauge field or generated by an Ising nematic quantum critical point. The one-loop dynamical exponent $z=3$ of these critical syste…

Physics of Superconductivity and MagnetismQuantum and electron transport phenomenaOrganic and Molecular Conductors Research

Ising Incommensurate Spin Resonance of CeCoIn5 : A Dynamical Precursor of the Q Phase

S. Raymond、G. Lapertot2015-07-16Physical Review Letters

It is shown through detailed inelastic neutron scattering experiments that the gapped collective magnetic excitation of the unconventional superconductor CeCoIn5, the spin resonance mode, is incommensurate and that the corresponding fluctuations are of an Ising nature. The incommensurate peak position of these fluctua…

Physics of Superconductivity and MagnetismRare-earth and actinide compoundsIron-based superconductors research

Mesenchymal Stem Cells as a Biological Drug for Heart Disease

Cristina Sanina、Joshua M. Hare2015-07-16Circulation Research

Cell-based treatment represents a new generation in the evolution of biological therapeutics. A prototypic cell-based therapy, the mesenchymal stem cell, has successfully entered phase III pivotal trials for heart failure, signifying adequate enabling safety and efficacy data from phase I and II trials. Successful pha…

Mesenchymal stem cell researchElectrospun Nanofibers in Biomedical ApplicationsTissue Engineering and Regenerative Medicine

Prelithiation Activates Li(Ni 0.5 Mn 0.3 Co 0.2 )O 2 for High Capacity and Excellent Cycling Stability

Zhongzhen Wu、Shunping Ji、Jiaxin Zheng 等 12 位作者2015-07-16Nano Letters

Transition metal oxide materials Li(NixMnyCoz)O2 (NMC) based on layered structures are expected to replace LiFePO4 in automotive Li-ion batteries because of their higher specific capacity and operating potential. However, the actual usable capacity is much lower than the promised theoretical value [Uchaker, E.; Cao, G…

Advancements in Battery MaterialsSupercapacitor Materials and FabricationAdvanced Battery Materials and Technologies

Cl-Doped ZnO Nanowire Arrays on 3D Graphene Foam with Highly Efficient Field Emission and Photocatalytic Properties

Dali Shao、Jian Gao、Guoqing Xin 等 9 位作者2015-07-16Small

An environmentally friendly, low-cost, and large-scale method is developed for fabrication of Cl-doped ZnO nanowire arrays (NWAs) on 3D graphene foam (Cl-ZnO NWAs/GF), and investigates its applications as a highly efficient field emitter and photocatalyst. The introduction of Cl-dopant in ZnO increases free electrons…

Advanced Photocatalysis TechniquesZnO doping and propertiesGa2O3 and related materials