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Fabrication of poly(γ-glutamic acid)-based biopolymer as the targeted drug delivery system with enhanced cytotoxicity to APN/CD13 over-expressed cells

Li Zhang、Jie Zhou、Ying Wang 等 7 位作者2015-01-01Figshare

Poly(γ-glutamic acid)-based targeted drug delivery system (PAMCN) targeting transmembrane metalloprotease aminopeptidase-N (APN/CD13) was fabricated and evaluated for the enhancement of targeting efficiency and cytotoxicity. The cisplatin (CDDP) loading content of PAMCN was about 36 ± 5% and PAMCN showed a sustainable…

Nanoparticle-Based Drug DeliveryBiopolymer Synthesis and ApplicationsRNA Interference and Gene Delivery

15-taxon

Md. Shamsuzzoha Bayzid2015-01-01Figshare

15-taxon simulated datasets

Diatoms and Algae ResearchSteroid Chemistry and BiochemistryMediterranean and Iberian flora and fauna

2.8 X-Ray Structure

Philip Bulsink2015-01-01Figshare

2.8 X-Ray structure

Advanced X-ray Imaging TechniquesX-ray Diffraction in Crystallography

Synthesis, Crystal Structure, and Luminescent Property of One 3D Porous Metal-Organic Framework with dmc Topology

Xuefeng Wei、Juan Miao、Lingling Shi2015-01-01Figshare

One new 3D porous metal-organic framework {[Zn(ox)0.5(trz)]·0.25H2O}n (1) [trz = 1,2,4-triazole, ox = oxalate] has been synthesized under hydrothermal conditions and characterized by elemental analysis, IR spectroscopy, single-crystal X-ray crystallography and powder X-ray diffraction (PXRD) analysis. The most remarka…

Metal-Organic Frameworks: Synthesis and ApplicationsX-ray Diffraction in CrystallographyNanocluster Synthesis and Applications

Figure 6

Victor Gurewich2015-01-01Figshare

Fig 6. The effect of the synergistic dose combination in plasma alone

Engineering and Material Science Research

Figure 3

Paul Isenring、Alexandre P. Garneau2015-01-01Figshare

Data for Figure 3

Engineering and Material Science Research

1p H4K20me1

Carolyn J. Brown2015-01-01Figshare

Green is RNA FISH using a probe against XIST RNA. Red is an anti-H4K20me1 antibody. Blue is DAPI. These images were used to calculate data shown in Table 2.

Metal complexes synthesis and propertiesMagnetism in coordination complexesDNA and Nucleic Acid Chemistry

Mucus-Inspired Biomaterial for more effective drug release

Thomas Crouzier、Connor V. Duffy、Laurent David2015-01-01Figshare

Mucins are biopolymer that assemble to into mucus, the thin gel that covers our eyes, nose, mouth, stomach, intestins, lungs, and female reproductive tract. Mucins are sticky molecules that protect us from infections. We assembled mucins into a hydrogel that would stick to therapteutic molecules to delays their releas…

Advanced Drug Delivery SystemsProteoglycans and glycosaminoglycans researchSupramolecular Self-Assembly in Materials

Gaussian Job Archive for C8H13ClN2O4

Henry S. Rzepa2015-01-01Figshare

Archive of work produced using the resources of the Imperial College High Performance Computing Service.

Organic Chemistry Cycloaddition ReactionsStructural and Chemical Analysis of Organic and Inorganic CompoundsSolid-state spectroscopy and crystallography

NanoPUZZLES ISA-TAB-Nano dataset: Data extracted from Puzyn et al. 2011 (DOI:10.1038/NNANO.2011.10)

Richard Marchese Robinson2015-01-01Figshare

This file is a ZIP archive which contains three different copies of an ISA-TAB-Nano dataset developed within the NanoPUZZLES EU project [http://www.nanopuzzles.eu]. The (meta)data in this dataset were primarily extracted from the following reference, with additional references consulted as indicated in the Investigati…

Machine Learning in Materials Science

Dispersion relations for MAPI deposited on a Si wafer

Laurie J. Phillips2015-01-01Figshare

Dispersion relations for MAPI deposited on a Si wafer. Measured using variable angle spectroscopic ellipsometry and fit using the following oscillators: - Tauc-Lorentz Eg 1.55 E 0 1.63 A0 23.9

Advanced ceramic materials synthesisSemiconductor materials and devicesSilicon Nanostructures and Photoluminescence

Gaussian Job Archive for C42H46N6O6

Henry S. Rzepa2015-01-01Figshare

Archive of work produced using the resources of the Imperial College High Performance Computing Service.

Photochromic and Fluorescence Chemistrybioluminescence and chemiluminescence research

Gaussian Job Archive for C6H16ClNO5

Henry S. Rzepa2015-01-01Figshare

Archive of work produced using the resources of the Imperial College High Performance Computing Service.

Molecular Spectroscopy and StructureElectron Spin Resonance StudiesSolid-state spectroscopy and crystallography

1p H3K9me3

Carolyn J. Brown2015-01-01Figshare

Green is RNA FISH using a probe against XIST RNA. Red is an anti-H3K9me3 antibody. Blue is DAPI. These images were used to calculate data shown in Table 2.

Magnetism in coordination complexesMetal complexes synthesis and propertiesBoron Compounds in Chemistry

Studying the structure of single-component ceramide bilayers with molecular dynamics simulations using different force fields

Nikolaos I. Papadimitriou、M.E. Kainourgiakis、Stelios Karozis 等 4 位作者2015-01-01Figshare

Molecular dynamics simulations are performed on a lipid bilayer that consists of ceramide NS 24:0 in an attempt to examine several structural and physicochemical properties of the specific system. The simulations are carried out with five different force fields (OPLS, GROMOS, BERGER, CHARMM and GAFF) in order to evalu…

Lipid Membrane Structure and BehaviorPolymer composites and self-healingPorphyrin and Phthalocyanine Chemistry

Repeated evolution of uniparental reproduction in Sellaphora (Bacillariophyceae)

Aloisie Poulíčková、Shinya Sato、Katharine Evans 等 5 位作者2015-01-01Figshare

Diatoms possess a remarkable life cycle in which cell size decreases slowly during vegetative cell division and then increases rapidly via special expanding cells called ‘auxospores’, which are usually formed as a result of biparental sexual reproduction. However, auxospores are sometimes produced by single unpaired c…

Aquatic Ecosystems and Phytoplankton DynamicsAnalytical chemistry methods developmentDiatoms and Algae Research

Gaussian Job Archive for C42H46N6O6

Henry S. Rzepa2015-01-01Figshare

Archive of work produced using the resources of the Imperial College High Performance Computing Service.

bioluminescence and chemiluminescence researchPhotochromic and Fluorescence Chemistry