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Improved brain uptake of peptide-based CNS drugs via alternative routes of administrations of its nanocarrier delivery systems: a promising strategy for CNS targeting delivery of peptides

Shuai Qian、Qianwen Wang、Zhong Zuo2014-09-06Expert Opinion on Drug Metabolism & Toxicology

INTRODUCTION: Recently, developing peptide-based drugs to treat CNS diseases has gained increasing attention in both academics and pharmaceutical industry. However, targeting delivery of peptides to brain is one of the most challenging problems faced in the treatment of CNS diseases. AREAS COVERED: After explaining th…

Nanoparticle-Based Drug DeliveryRNA Interference and Gene DeliveryAdvanced Drug Delivery Systems

Aberrant Assembly Complexes of the Reaction Center Light-harvesting 1 PufX (RC-LH1-PufX) Core Complex of Rhodobacter sphaeroides Imaged by Atomic Force Microscopy

John D. Olsen、Peter G. Adams、Philip J. Jackson 等 6 位作者2014-09-06Journal of Biological Chemistry

In the purple phototrophic bacterium Rhodobacter sphaeroides, many protein complexes congregate within the membrane to form operational photosynthetic units consisting of arrays of light-harvesting LH2 complexes and monomeric and dimeric reaction center (RC)-light-harvesting 1 (LH1)-PufX "core" complexes. Each half of…

Photosynthetic Processes and MechanismsEnzyme Structure and FunctionSpectroscopy and Quantum Chemical Studies

Survival of Escherichia coli Cells on Solid Copper Surfaces Is Increased by Glutathione

Cornelia Große、Grit Schleuder、Christin Schmole 等 4 位作者2014-09-06Applied and Environmental Microbiology

Bacteria are rapidly killed on solid copper surfaces, so this material could be useful to limit the spread of multiple-drug-resistant bacteria in hospitals. In Escherichia coli, the DNA-protecting Dps protein and the NADH:ubiquinone oxidoreductase II Ndh were not involved in tolerance to copper ions or survival on sol…

Nanoparticles: synthesis and applicationsHeavy Metal Exposure and ToxicityTrace Elements in Health

Silver versus white sheet as a back reflector for microcrystalline silicon solar cells deposited on LPCVD‐ZnO electrodes of various textures

Rami Khazaka、Etienne Moulin、Mathieu Boccard 等 8 位作者2014-09-06Progress in Photovoltaics Research and Applications

Abstract We compare the performance of two back reflector designs on the optoelectrical properties of microcrystalline silicon solar cells. The first one consists of a 5‐µm‐thick low‐pressure chemical vapor deposition (LPCVD)‐ZnO electrode combined with a white sheet; the second one incorporates an Ag reflector deposi…

Thin-Film Transistor TechnologiesSilicon and Solar Cell TechnologiesSilicon Nanostructures and Photoluminescence

Controlling methanogenesis and improving power production of microbial fuel cell by lauric acid dosing

P. P. Rajesh、Md Tabish Noori、Makarand M. Ghangrekar2014-09-06Water Science & Technology

Methanogens compete with anodophiles for substrate and thus reduce the power generation and coulombic efficiency (CE) of the microbial fuel cell (MFC). Performance of a baked clayware membrane MFC inoculated with mixed anaerobic sludge pretreated with lauric acid was investigated in order to enhance power recovery by…

Supercapacitor Materials and FabricationElectrochemical sensors and biosensorsMicrobial Fuel Cells and Bioremediation

Metabolic engineering ofCorynebacterium glutamicumstrain ATCC13032 to produce l ‐methionine

Tianyu Qin、Xiaoqing Hu、Jinyu Hu 等 4 位作者2014-09-06Biotechnology and Applied Biochemistry

L-Methionine-producing strain QW102/pJYW-4-hom(m) -lysC(m) -brnFE was developed from Corynebacterium glutamicum strain ATCC13032, using metabolic engineering strategies. These strategies involved (i) deletion of the gene thrB encoding homoserine kinase to increase the precursor supply, (ii) deletion of the gene mcbR e…

Biofuel production and bioconversionMicrobial Metabolic Engineering and BioproductionEnzyme Structure and Function

New trends in vinyl ester resins

Shipra Jaswal、Bharti Gaur2014-09-06Reviews in Chemical Engineering

Abstract Vinyl ester resins (VERs) are high-performance unsaturated resins derived by the addition reaction of various epoxide resins with α-β unsaturated carboxylic acids. These resins have always been classified under unsaturated polyester resins. However, VERs have remarkable corrosion resistance and superior physi…

Polymer composites and self-healingEpoxy Resin Curing ProcessesSynthesis and properties of polymers

Glutathione Reductase-Mediated Synthesis of Tellurium-Containing Nanostructures Exhibiting Antibacterial Properties

Benoı̂t Pugin、Fabián A. Cornejo、Pablo Muñoz-Díaz 等 7 位作者2014-09-06Applied and Environmental Microbiology

Tellurium, a metalloid belonging to group 16 of the periodic table, displays very interesting physical and chemical properties and lately has attracted significant attention for its use in nanotechnology. In this context, the use of microorganisms for synthesizing nanostructures emerges as an eco-friendly and exciting…

Nanoparticles: synthesis and applicationsSelenium in Biological SystemsOrganoselenium and organotellurium chemistry

2ZrO 2 ·Y 2 O 3 Thermal Barrier Coatings Resistant to Degradation by Molten CMAS : Part II , Interactions with Sand and Fly Ash

Amanda R. Krause、Hector F. Garcés、Bilge S. Senturk 等 4 位作者2014-09-06Journal of the American Ceramic Society

Based on the application of OB considerations (Part I) to various major thermal barrier coating ( TBC ) compositions and two types of important calcium–magnesium–alumino–silicates ( CMAS )—desert sand and fly ash—the 2 ZrO 2 · Y 2 O 3 solid solution (ss) TBC composition, with high CMAS ‐resistance potential, is chosen…

Advanced ceramic materials synthesisHigh-Temperature Coating BehaviorsNuclear Materials and Properties

Grain refinement of Al–Si alloys by Nb–B inoculation. Part II: Application to commercial alloys

L. Bolzoni、Mariusz Nowak、N. Hari Babu2014-09-06Materials & Design (1980-2015)

The potency of Nb–B inoculation for the refinement of Al–Si cast alloy has been demonstrated in Part I of this work by the systematic analysis of binary Al–xSi alloys (where x = 1–10 wt.%). In Part II of this work the effect of Nb–B inoculation on commercial Al–Si alloys is assessed. Specifically, hypo-eutectic alloys…

Microstructure and mechanical propertiesAluminum Alloy Microstructure PropertiesAluminum Alloys Composites Properties

Multiwall carbon nanotubes-poly(diallyldimethylammonium chloride)-graphene hybrid composite film for simultaneous determination of catechol and hydroquinone

Daimin Song、Jianfei Xia、Feifei Zhang 等 10 位作者2014-09-06Sensors and Actuators B Chemical

A multiwall carbon nanotubes-poly(diallyldimethylammonium chloride)-graphene modified glassy carbon electrode (MWCNTs-PDDA-GR/GCE) has been fabricated and used for simultaneous determination of catechol (CC) and hydroquinone (HQ). Transmission electron microscopy (TEM) and electrochemical impedance spectroscopy (EIS)…

Electrochemical sensors and biosensorsConducting polymers and applicationsElectrochemical Analysis and Applications

Grain refinement of Al–Si alloys by Nb–B inoculation. Part I: Concept development and effect on binary alloys

Mariusz Nowak、L. Bolzoni、N. Hari Babu2014-09-06Materials & Design (1980-2015)

The effect of Nb–B inoculation on Al–Si alloys for their grain refinement has been studied through the analysis of binary Al–xSi (where x = 1–10 wt.%) to avoid possible effects of other alloying elements. In Part I of this work the concept development of the Nb–B inoculation is discussed in detail on the basis of the…

Microstructure and mechanical propertiesAluminum Alloy Microstructure PropertiesAluminum Alloys Composites Properties

Evaluation of dairy industry wastewater treatment and simultaneous bioelectricity generation in a catalyst-less and mediator-less membrane microbial fuel cell

Hossein Jafari Mansoorian、Amir Hossein Mahvi、Ahmad Jonidi Jafari 等 4 位作者2014-09-06Journal of Saudi Chemical Society

Increased human activity and consumption of natural energy resources have led to decline in fossil fuel. These current methods of energy production are not compatible with the environment. In this study catalyst-less and mediator-less membrane microbial fuel cell (CAML-MMFC) represents a new method for simultaneous da…

Supercapacitor Materials and FabricationElectrochemical sensors and biosensorsMicrobial Fuel Cells and Bioremediation

Transcranial Focused Ultrasound Modulates Intrinsic and Evoked EEG Dynamics

Jerel K. Mueller、Wynn Legon、Alexander Opitz 等 5 位作者2014-09-06Brain stimulation

BACKGROUND: The integration of EEG recordings and transcranial neuromodulation has provided a useful construct for noninvasively investigating the modification of human brain circuit activity. Recent evidence has demonstrated that focused ultrasound can be targeted through the human skull to affect the amplitude of so…

Ultrasound and Hyperthermia ApplicationsUltrasound and Cavitation PhenomenaPhotoacoustic and Ultrasonic Imaging

Hydrothermal synthesis of surface-modified copper oxide-doped zinc oxide nanoparticles for degradation of acid black 1: Modeling and optimization by response surface methodology

Kamal Salehi、Hiua Daraei、Pari Teymouri 等 5 位作者2014-09-06DOAJ (DOAJ: Directory of Open Access Journals)

Dyes are widely used in various industries most of them are not readily biodegradable and are consisted of number of toxic, mutagenic, and carcinogenic compounds. Therefore, it is essential to remove them from effluent before their discharge to the environment. The objective of this investigation was to synthesize cop…

TiO2 Photocatalysis and Solar CellsNanoparticles: synthesis and applicationsCopper-based nanomaterials and applications

To Study the mechanical properties of coconut coir fiber reinforced with epoxy resin AW 106 & HV 953 IN

Journal Ijmer、Abdul Nazeer2014-09-06OpenAlex

In this study the Mechanical Properties of Coconut coir Fiber is reinforced with epoxy resin of different lengths (5mm,10mm,15mm) and coir fibers by treating the fiber with NaOH by fraction of 5 % are studied here. All samples were made using hand layup technique and specimens were prepared as per ASTM standard D3039.…

Natural Fiber Reinforced CompositesFluid Dynamics Simulations and InteractionsEngineering Structural Analysis Methods

Novel elastomeric fibrous networks produced from poly(xylitol sebacate)2:5 by core/shell electrospinning: Fabrication and mechanical properties

Yuan Li、George A. Thouas、Qizhi Chen2014-09-06Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials

Fabrication of nonlinear elastic materials that resemble biological tissues remains a challenge in biomaterials research. Here, a new fabrication protocol to produce elastomeric fibrous scaffolds was established, using the core/shell electrospinning technique. A prepolymer of poly(xylitol sebacate) with a 2:5mol ratio…

Bone Tissue Engineering Materialsbiodegradable polymer synthesis and propertiesElectrospun Nanofibers in Biomedical Applications

Complexes of tetraethylthiuram disulphide with group 12 metals: single-source precursor in metal sulphide nanoparticles’ synthesis

Satyendra N. Shukla、Pratiksha Gaur、Nidhi Rai2014-09-06Applied Nanoscience

Six new complexes of Zn(II), Cd(II) and Hg(II) with sulphur containing ligand, tetraethylthiuram disulphide in 2:2 and 1:4 ratio have been synthesized. The resulting complexes have been characterized on the basis of molar conductance measurement, elemental analyses, FT-IR, 1 H-NMR, and FAB/ESI-mass studies. The comple…

Gold and Silver Nanoparticles Synthesis and ApplicationsQuantum Dots Synthesis And PropertiesChalcogenide Semiconductor Thin Films

Light harvesting with metasurfaces: applications to sensors and energy generation

David T. Crouse、Eli Lansey、Isroel M. Mandel 等 4 位作者2014-09-06Applied Physics A

Metasurfaces have been receiving increasing interest due to the complex array of radiation controlling properties that are possible with single-layer films. This talk and work will focus on metasurfaces that can provide light filtering according to wavelength, polarization, and other properties of an incident beam, an…

Metamaterials and Metasurfaces ApplicationsPlasmonic and Surface Plasmon ResearchThermal Radiation and Cooling Technologies

Characterization of CVD Bonded Tyranno® Fibers Oxidized at High Temperatures

Natalia Remirez de Esparza、N. Cocera、Lexuri Vázquez 等 6 位作者2014-09-06Journal of the American Ceramic Society

The oxidation of highly porous ceramic matrix composites ( PCMC s) based on different Tyranno ® fibers has been analyzed by means of thermogravimetry and electron microscopy. Both uncoated fibers and PCMC materials exhibit parabolic kinetics between 900°C and 1250°C, these being faster for Ti‐doped than for Zr‐doped T…

Advanced ceramic materials synthesisHigh-Temperature Coating BehaviorsAdvanced materials and composites