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Advanced in vitro systems for efficacy and toxicity testing in nanomedicine

Maria Rita Fabbrizi、Tracey Duff、Jo Oliver 等 4 位作者2014-08-23European Journal of Nanomedicine

Abstract The use of nanoparticles (NPs) in nanomedicine is becoming an established therapeutic strategy for transport and delivery of bioactive molecules across biological barriers to elicit a specific cytological response in a target cell population. The utility of NP-derivatised nanomedicines and their potential the…

Nanoparticle-Based Drug DeliveryNanoparticles: synthesis and applications3D Printing in Biomedical Research

A reduced model for domain walls in soft ferromagnetic films at the cross-over from symmetric to asymmetric wall types

Lukas Döring、Radu Ignat、Félix Otto2014-08-23Journal of the European Mathematical Society

We study the Landau-Lifshitz model for the energy of multi-scale transition layers – called "domain walls'' – in soft ferromagnetic films. Domain walls separate domains of constant magnetization vectors m^\pm_\alpha\in\mathbb{S}^2 that differ by an angle 2\alpha . Assuming translation invariance tangential to the wall…

Advanced Numerical Methods in Computational MathematicsMagnetic Properties and ApplicationsAdvanced Mathematical Modeling in Engineering

Scale-up synthesis and characterization of 2,6-diamino-3,5-dinitropyrazine-1-oxide

Haibin Wang、Yanhong Wang、Yongxiang Li 等 5 位作者2014-08-23Defence Technology

2,6-diamino-3,5-dinitropyrazine-1-oxide (ANPZO), as an insensitive high explosive, with a high yield and excellent purity has been prepared at pilot plant scale by an improved method. The synthesized ANPZO is characterized by IR, laser granularity measurement, SEM and HPLC. The particle analysis revealed that the impr…

Energetic Materials and CombustionThermal and Kinetic AnalysisRocket and propulsion systems research

Extraction of Rotational Correlation Times from Noisy Single Molecule Fluorescence Trajectories

Dat Tien Hoang、Keewook Paeng、Heungman Park 等 5 位作者2014-08-23Analytical Chemistry

Monitoring single molecule probe rotations is an increasingly common approach to studying dynamics of complex systems, including supercooled liquids. Even with advances in fluorophore design and detector sensitivity, such measurements typically exhibit low signal to noise and signal to background ratios. Here, we simu…

Material Dynamics and PropertiesAdvanced Fluorescence Microscopy TechniquesPhotochemistry and Electron Transfer Studies

Kinetic study of uranium residue dissolution in ammonium carbonate media

Bundjoko Kweto、D.R. Groot、Elizabeth Stassen 等 5 位作者2014-08-23Journal of Radioanalytical and Nuclear Chemistry

The purpose of this study was to determine the kinetics of the dissolution of a uranium residue in ammonium carbonate media. The residue is generated in the production of medical isotopes. The effects of parameters, such as varying peroxide and carbonate concentrations, dissolution time as well as temperature on the e…

Radioactive element chemistry and processingNuclear Materials and PropertiesNuclear materials and radiation effects

Evaluation of radiation dose due to naturally occurring radionuclides in rock samples of different origins collected from Azad Kashmir

Muhammad Rafique、Abdul Rehman Khan、Abdul Jabbar 等 8 位作者2014-08-23Russian Geology and Geophysics

Abstract The state of Azad Kashmir is rich in three types of rocks, namely, sedimentary, metamorphic, and igneous rocks. These rocks contain extensive deposits of graphite, marble, limestone, quartzite, granite, dolerite, and sandstone, which are widely used for the construction of dwellings in Azad Kashmir and Pakist…

Radiation Dose and ImagingRadioactivity and Radon MeasurementsGraphite, nuclear technology, radiation studies

Propionate stimulates pyruvate oxidation in the presence of acetate

Colin Purmal、Blanka Kucejová、A. Dean Sherry 等 6 位作者2014-08-23American Journal of Physiology-Heart and Circulatory Physiology

Flux through pyruvate dehydrogenase (PDH) in the heart may be reduced by various forms of injury to the myocardium, or by oxidation of alternative substrates in normal heart tissue. It is important to distinguish these two mechanisms because imaging of flux through PDH based on the appearance of hyperpolarized (HP) [(…

Advanced MRI Techniques and ApplicationsAdvanced NMR Techniques and ApplicationsSolid-state spectroscopy and crystallography

Hyperpolarized [1,3‐13C2]ethyl acetoacetate is a novel diagnostic metabolic marker of liver cancer

Pernille Rose Jensen、Sonia Colombo Serra、Luigi Miragoli 等 9 位作者2014-08-23International Journal of Cancer

An increased prevalence of liver diseases such as hepatitis C and nonalcoholic fatty liver results in an augmented incidence of the most common form of liver cancer, hepatocellular carcinoma (HCC). HCC is most often found in the cirrhotic liver and it can therefore be challenging to rely on anatomical information alon…

Advanced NMR Techniques and ApplicationsSolid-state spectroscopy and crystallographyElectron Spin Resonance Studies

A critical assessment of the “stable indenter velocity” method for obtaining the creep stress exponent from indentation data

J. Dean、J. E. Campbell、G. Aldrich-Smith 等 4 位作者2014-08-23Acta Materialia

A technique for evaluating the (steady-state) creep stress exponent ( n ) from indentation data has come into common use over recent years. It involves monitoring the indenter displacement history under constant load and assuming that, once its velocity has stabilized, the system is in a quasi-steady state, with Stage…

Advanced ceramic materials synthesisMetal and Thin Film MechanicsMechanical stress and fatigue analysis

Implementation of industrial waste ferrochrome slag in conventional and low cement castables: Effect of calcined alumina

Pattem Hemanth Kumar、A. Srivastava、Vijay Kumar 等 4 位作者2014-08-23Journal of Asian Ceramic Societies

A new class of conventional and low-cement ferrochrome slag-based castables were prepared from 40 wt.% ferrochrome slag and 45 wt.% calcined bauxite. Rest fraction varied between high alumina cement (HAC) acting as hydraulic binder and calcined alumina as pore filling additive. Standard ASTM size briquettes were prepa…

Concrete and Cement Materials ResearchRecycling and utilization of industrial and municipal waste in materials productionMagnesium Oxide Properties and Applications

Nonphospholipid Fluid Liposomes with Switchable Photocontrolled Release

Zhong‐Kai Cui、Thida Phoeung、Pierre-Antoine Rousseau 等 7 位作者2014-08-23Langmuir

We created novel nonphospholipid photosensitive liposomes from a mixture of a monoacylated azobenzene amphiphile (AzoC10N(+)) and cholesterol sulfate (Schol). This system belongs to the family of sterol-enriched nonphospholipid liposomes that were shown to form stable large unilamellar vesicles (LUVs) with enhanced im…

Lipid Membrane Structure and BehaviorPorphyrin and Phthalocyanine ChemistrySupramolecular Self-Assembly in Materials

Effect of Substrate Mechanics on Cardiomyocyte Maturation and Growth

Marwa Tallawi、Ranjana Rai、Aldo R. Boccaccini 等 4 位作者2014-08-23Tissue Engineering Part B Reviews

Cardiac tissue engineering constructs are a promising therapeutic treatment for myocardial infarction, which is one of the leading causes of death. In order to further advance the development and regeneration of engineered cardiac tissues using biomaterial platforms, it is important to have a complete overview of the…

Electrospun Nanofibers in Biomedical Applications3D Printing in Biomedical ResearchTissue Engineering and Regenerative Medicine

Newly Identified Thermostable Esterase from Sulfobacillus acidophilus: Properties and Performance in Phthalate Ester Degradation

Xiaoyan Zhang、Xiang Fan、Yongjun Qiu 等 7 位作者2014-08-23Applied and Environmental Microbiology

EstS1, a newly identified thermostable esterase from Sulfobacillus acidophilus DSM10332, was heterologously expressed in Escherichia coli and shown to enzymatically degrade phthalate esters (PAEs) to their corresponding monoalkyl PAEs. The optimal pH and temperature of the esterase were found to be 8.0 and 70°C, respe…

Enzyme Catalysis and Immobilizationbiodegradable polymer synthesis and propertiesMicrobial Metabolic Engineering and Bioproduction

Probing Crystal Growth of ε- and α-CL-20 Polymorphs via Metastable Phase Transition Using Microscopy and Vibrational Spectroscopy

Mrinal Kanti Ghosh、V. Venkatesan、Snehal Mandave 等 7 位作者2014-08-23Crystal Growth & Design

This article presents evidence of a possible route to the formation of ε- and α-polymorphic phases of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) studied through CL-20 solution using a reverse and normal precipitation method. Reverse precipitation with instant addition facilitated the opportunit…

Energetic Materials and CombustionThermal and Kinetic AnalysisSynthesis and Characterization of Heterocyclic Compounds

Modeling the Rheology of Polymer Melts and Solutions

Ronald G. Larson、Priyanka S. Desai2014-08-23Annual Review of Fluid Mechanics

We review constitutive modeling of solutions and melts of linear polymers, focusing on changes in rheological behavior in shear and extensional flow as the concentration increases from unentangled dilute, to entangled, to dense melt. The rheological changes are captured by constitutive equations, prototypes of which a…

Polymer crystallization and propertiesRheology and Fluid Dynamics StudiesPolymer Foaming and Composites

Combined treatment technology based on synergism between hydrodynamic cavitation and advanced oxidation processes

Parag R. Gogate、Pankaj N. Patil2014-08-23Ultrasonics Sonochemistry

The present work highlights the novel approach of combination of hydrodynamic cavitation and advanced oxidation processes for wastewater treatment. The initial part of the work concentrates on the critical analysis of the literature related to the combined approaches based on hydrodynamic cavitation followed by a case…

Advanced oxidation water treatmentUltrasound and Cavitation PhenomenaEnvironmental remediation with nanomaterials

In-situ cryocrystallization of 1,2-dimethyl-3-nitrobenzene and 2,4-dimethyl-1-nitrobenzene

Hazel A. Sparkes、H.J. ROMAN SAGE、Dmitry S. Yufit2014-08-23Acta Crystallographica Section C Structural Chemistry

The crystal structures of 1,2-dimethyl-3-nitrobenzene, C8H9NO2, and 2,4-dimethyl-1-nitrobenzene, C8H9NO2, which are liquids at room temperature, have been obtained through in-situ cryocrystallization. Weak C-H...O and also π-π interactions are present in both crystal structures.

Crystallography and molecular interactionsEnzyme Structure and FunctionCrystallization and Solubility Studies

Fast and extracellular synthesis of zinc oxide nanocrystals using the novel isolated yeast strain Candida sp. MY2

Morahem Ashengroph2014-08-23Cellular and Molecular Researches #R##N#(Iranian Journal of Biology)

Microorganisms as potent eco-friendly green nanofactories have the potential to control the size and shape of biological nanostructures. Zinc oxide nanoparticles have found much potential in pharmaceuticals, biological sciences, biomedical sciences and therapy diagnosis. In the current investigation, the native yeast…

Nanoparticles: synthesis and applications

Pyrolysis of cyclo-aromatic diesters

Marta Worzakowska2014-08-23Journal of Thermal Analysis and Calorimetry

Studies on the pyrolysis of cyclo-aromatic diesters derivatives of 3-phenylprop-2-en-1-ol are presented. The diesters are obtained during catalyzed esterification process of a stoichiometric ratio of 3-phenylprop-2-en-1-ol with suitable cycloaliphatic or aromatic acid anhydride in the solvent-free medium. As an acid a…

Thermal and Kinetic AnalysisStructural and Chemical Analysis of Organic and Inorganic CompoundsChemical Thermodynamics and Molecular Structure

High thermal conductive m‐xylylenediamine functionalized multiwall carbon nanotubes/epoxy resin composites

Fan Xie、Shuhua Qi、Rui Yang 等 4 位作者2014-08-23Journal of Applied Polymer Science

ABSTRACT In this study, multiwall carbon nanotubes (MWNTs) functionalized by m‐xylylenediamine is used as thermal conductive fillers to improve their dispersibility in epoxy resin and the thermal conductivity of the MWNTs/bisphenol‐A glycidol ether epoxy resin composites. Functionalization with amine groups of MWNTs i…

Carbon Nanotubes in CompositesThermal properties of materialsTribology and Wear Analysis