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Lipid based Nanocarriers for Oral Delivery of Cancer Chemotherapeutics: An Insight in the Intestinal Lymphatic Transport

Javed Ahmad、Kanchan Kohli、Showkat R. Mir 等 4 位作者2013-04-01Drug Delivery Letters

Mostly anticancer drugs are given as IV infusions, which result in hypertensive reactions due to formulation excipients. Their oral bioavailability is poor or variable due to high liver metabolism, poor aqueous solubility, high Pgp effluxing and macron size. To promote the oral drug delivery of these potential chemoth…

Nanoparticle-Based Drug DeliveryCurcumin's Biomedical ApplicationsChemical Reactions and Isotopes

Nuclear Thermal Propulsion: Past Accomplishments, Present Efforts, and a Look Ahead

Stanley K. Borowski2013-04-01Journal of Aerospace Engineering

The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) has been actively involved in nuclear thermal propulsion (NTP) technology development, mission, engine, and vehicle design dating back to the Rover and Nuclear Engine for Rocket Vehicle Applications programs. This technology was succe…

Nuclear reactor physics and engineeringGraphite, nuclear technology, radiation studiesNuclear and radioactivity studies

Targeting Multiplicity: The Key Factor for Anti-Cancer Nanoparticles

Magali Gary‐Bobo、Ophélie Vaillant、Marie Maynadier 等 12 位作者2013-04-01Current Medicinal Chemistry

In this mini-review, we focus on different strategies to bring nanotools specifically to cancer cells. We discuss about a better targeting of tumor, combining the characteristics of tumor environment, the increase in nanoparticles life time, the biomarkers overexpressed on cancer cells and different physical methods f…

Nanoparticle-Based Drug DeliveryCancer Research and TreatmentsCancer Research and Treatment

Physical Guiding Principles for High Quality Resistive Random Access Memory Stack with Al2O3 Insertion Layer

Moon Young Yang、Katsumasa Kamiya、Blanka Magyari-Köpe 等 8 位作者2013-04-01Japanese Journal of Applied Physics

We theoretically clarified the atomistic role of the Al2O3 oxygen vacancy (VO) barrier layer in advanced ReRAM stacks. We found that VO filament formation in Al2O3 can be controlled by applying voltage when the Al2O3 layer is in contact with VO source layer such as Hf, although VO formation in Al2O3 is difficult in us…

Advanced Memory and Neural ComputingElectronic and Structural Properties of OxidesFerroelectric and Negative Capacitance Devices

Effect of temperatures on electrodeposition of CoWP films

Ying Yu、Mingming He、M. G. Li 等 6 位作者2013-04-01Surface Engineering

CoWP alloy films were prepared by a typical citrate system electrodeposition on a copper substrate. The paper investigated effects of different temperatures on codeposition mechanism, magnetic property, component and structure of CoWP alloy films during the electrodeposition process. With the increase in temperatures,…

Electrodeposition and Electroless CoatingsCopper Interconnects and ReliabilitySemiconductor materials and interfaces

The Peculiarities of the Electrical Conductivity of LiNbO3 Crystals, Reduced in Hydrogen

A. V. Yatsenko、A. S. Pritulenko、S. V. Yevdokimov 等 5 位作者2013-04-01Diffusion and defect data, solid state data. Part B, Solid state phenomena/Solid state phenomena

The low-frequency impedance spectroscopy method has been used to investigate the electrical conductivity peculiarities of lithium niobate (LN) crystals reduced in hydrogen. It has been found that the activation energy value of the dark electrical conductivity of such crystals in a temperature range of 288...370 К is e…

Photorefractive and Nonlinear OpticsSolid-state spectroscopy and crystallographyOptical and Acousto-Optic Technologies

Coherent spin dynamics of different density high mobility two-dimensional electron gas in a GaAs quantum well

A. V. Larionov、A. S. Zhuravlev2013-04-01Journal of Experimental and Theoretical Physics Letters

We have addressed the dependence of quasi-two-dimensional electron spin dephasing time on the electron gas density in a 17-nm GaAs quantum well using the time-resolved magneto-optical Kerr effect. A superlinear increase in the electron dephasing time with decreasing electron density has been found. The degree of elect…

Semiconductor Quantum Structures and DevicesQuantum and electron transport phenomenaElectronic and Structural Properties of Oxides

Quasi-two-dimensional Ag nanoparticle formation in silica by Xe ion irradiation and subsequent Ag ion implantation

Jun Wang、Guangyi Jia、Xiaoyu Mu 等 4 位作者2013-04-01Applied Physics Letters

Ag nanoparticles were fabricated in silica by Xe ion irradiation and subsequent Ag ion implantation, which distributed in a depth range from 4.8 to 14.3 nm, rather than dispersed from surface to a depth of 24.7 nm when no irradiation was made in advance. In addition, the suppression of Ag implants' sputtering loss was…

Quantum Dots Synthesis And PropertiesNonlinear Optical Materials StudiesIon-surface interactions and analysis

Photoluminescence Enhancement of InAs(Bi) Quantum Dots by Bi Clustering

D.F. Reyes、D. González、F. Bastiman 等 10 位作者2013-04-01Applied Physics Express

The distribution of bismuth in InAs 1- x Bi x /GaAs quantum dots is analyzed by atomic-column resolution electron microscopy and imaging simulation techniques. A random Bi distribution is measured in the case of <0.03 ML/s Bi flux during the InAs growth with no significant variations in the shape or size of quantum do…

Semiconductor Quantum Structures and DevicesQuantum Dots Synthesis And PropertiesAdvanced Semiconductor Detectors and Materials

THERAPEUTIC APPLICATION OF NANOTECHNOLOGY IN CARDIOVASCULAR AND PULMONARY REGENERATION

Young Wook Chun、Spencer W. Crowder、Steven C. Mehl 等 6 位作者2013-04-01Computational and Structural Biotechnology Journal

Recently, a wide range of nanotechnologies has been approached for material modification by realizing the fact that the extracellular matrix (ECM) consists of nanoscale components and exhibits nanoscale architectures. Moreover, cell-cell and cell- ECM interactions actively occur on the nanoscale and ultimately play la…

Bone Tissue Engineering MaterialsElectrospun Nanofibers in Biomedical ApplicationsTissue Engineering and Regenerative Medicine

Comparative analysis of mechanical properties of Si substrates processed by different routes

Sylvain Gouttebroze、H.I. Lange、Xiang Ma 等 8 位作者2013-04-01physica status solidi (a)

Abstract The purpose of this work is to check the potential of innovative processes for the Si wafers production toward the solar cell industry. Studies have been focused on a comparative analysis of mechanical properties of such wafers, since: (i) reduced wafer strength leads to a high breakage rate during subsequent…

Advanced ceramic materials synthesisSilicon and Solar Cell TechnologiesAdvanced Surface Polishing Techniques

Combination of Ozonation and Hydrogen Peroxide Bleaching for Linen Fabrics: Optimization of the Process Using Experimental Design Technique

Seher Perinçek、Kerim Duran、Ayşegül Körlü2013-04-01Ozone Science and Engineering

It is well known that ozone can be used as a bleaching agent for cellulosic textile materials. In the context of this study, investigations were undertaken to optimize bleaching of linen fabrics using Box-Behnken Experimental Design. The bleaching process involved two distinct steps where linen fabrics were ozonated u…

Polymer composites and self-healingLignin and Wood ChemistryDyeing and Modifying Textile Fibers

Through-focus EUV multilayer defect repair with nanomachining

Gregory McIntyre、Emily Gallagher、Tod Robinson 等 9 位作者2013-04-01Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

Defects within the multilayer mirrors of EUV photomasks have been a leading challenge for EUV lithography for quite some time. By creating non-planar surfaces, they distort both the amplitude and phase of reflected light. Amplitude errors generally create a CD error on wafer, whereas phase errors tend to cause asymmet…

Advancements in Photolithography TechniquesElectron and X-Ray Spectroscopy TechniquesIntegrated Circuits and Semiconductor Failure Analysis

Adsorption of methylene blue dye onto activated carbons based on agricultural by-products: equilibrium and kinetic studies

Zacharias Ioannou、J. Simitzis2013-04-01Water Science & Technology

Mixtures of novolac resin and olive stone biomass (20/80 and 40/60 w/w) were cured, pyrolyzed up to 1,000 °C and activated with CO2 under a continuous flow operation (named N20B-cCa and N40B-cCa respectively). Commercial activated charcoal was similarly re-activated with CO2 and used for comparison reasons (AC-a). The…

Adsorption and biosorption for pollutant removalGraphene research and applicationsRecycling and Waste Management Techniques

Root cause analysis of bowl-mill pinion shaft failures

A.H.V. Pavan、K.S.N. Vikrant、M. Swamy 等 4 位作者2013-04-01Case Studies in Engineering Failure Analysis

Pinion shafts made of 18CrNiMo7-6 material, are used for transmitting torque from motor to gear box used in bowl mills of fossil fuel fired power plants. This work elucidates the metallurgical investigation that was carried out on a failed pinion shaft for analyzing the cause for failure. Fractography revealed the ini…

Hydrogen embrittlement and corrosion behaviors in metalsMechanical Failure Analysis and SimulationEngineering Diagnostics and Reliability

Mechanical spectroscopy of Al-Mg alloys

I.S. Golovin、А. С. Бычков、S. V. Medvedeva 等 5 位作者2013-04-01The Physics of Metals and Metallography

The internal friction of deformed, annealed, and quenched Al-Mg alloys with Mg contents of 0–12 wt % has been studied as a function of temperature. The measurements have been performed in the range of 25–580°C at 0.3–30 Hz using a DMA Q800 TA Instruments dynamic mechanical analyzer at the maximum amplitude of deformat…

Microstructure and mechanical propertiesCorrosion Behavior and InhibitionAluminum Alloy Microstructure Properties

Web Tools for Predicting Metal Binding Sites in Proteins

V. M. Sobolev、Marvin Edelman2013-04-01Israel Journal of Chemistry

Abstract Approximately one third of proteins bind metal ions for stability and/or enzymatic function. However, on a structural level, only a small fraction of binding sites have been resolved. Metal binding site predictions can serve as a first step in putative function assignment for many unannotated proteins. Sequen…

Protein Structure and DynamicsRNA and protein synthesis mechanismsEnzyme Structure and Function

Utilization of surface energetics approach to Understand protein interaction to ceramic hydroxyapatite

Muhammad Aasım、Noor Shad Bibi、Rami Reddy Vennapusa 等 4 位作者2013-04-01Journal of Chemical Technology & Biotechnology

Abstract Background A surface thermodynamics approach can be utilized to understand protein interaction during adsorption chromatography. Ceramic hydroxyapatite has been widely used in the purification of biomolecules during downstream bio‐processing. Protein interaction with this adsorbent is a complicated process. R…

Protein purification and stabilityCrystallization and Solubility Studiesthermodynamics and calorimetric analyses

Vacancy Assisted Li Intercalation in Crystalline Si as Anode Materials for Lithium Ion Batteries

Jinmei Huang、Zhiqiang Wang、Xin Gong 等 12 位作者2013-04-01International Journal of Electrochemical Science

Silicon is one important candidate as anode materials for next generation lithium ion batteries because of its extremely high specific capacity (4200mAh/g). In this paper, we show from first principles calculations that vacancies play important role in the beginning of the lithiation process of crystalline silicon. Wi…

Advancements in Battery MaterialsGraphene research and applicationsSemiconductor materials and interfaces

Evaluation of plastic materials for range shifting, range compensation, and solid‐phantom dosimetry in carbon‐ion radiotherapy

Nobuyuki Kanematsu、Yusuke Koba、Risa Ogata2013-04-01Medical Physics

PURPOSE: Beam range control is the essence of radiotherapy with heavy charged particles. In conventional broad-beam delivery, fine range adjustment is achieved by insertion of range shifting and compensating materials. In dosimetry, solid phantoms are often used for convenience. These materials should ideally be equiv…

Advanced Radiotherapy TechniquesRadiation Therapy and DosimetryRadiation Shielding Materials Analysis