Materials Literature
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Monolayers of transition metal dichalcogenides (TMDCs) are atomically thin direct-gap semiconductors with potential applications in nanoelectronics, optoelectronics, and electrochemical sensing. Recent theoretical and experimental efforts suggest that they are ideal systems for exploiting the valley degrees of freedom…
Liposomes, sphere-shaped vesicles consisting of one or more phospholipid bilayers, were first described in the mid-60s. Today, they are a very useful reproduction, reagent, and tool in various scientific disciplines, including mathematics and theoretical physics, biophysics, chemistry, colloid science, biochemistry, a…
Circulating tumor cells (CTCs) in the blood of cancer patients are related to cancer progress and metastasis. CTCs can be isolated from non-epithelial, hematological cells using one of antibodies against epithelial cell surface markers called epithelial-cell-adhesion-molecule (EpCAM), human-epidermal-growth-factor- re…
Nowadays special attention has been given to materials capable of \ngenerating visible light by conversion of near infrared photons \n(upconversion) for save-energy technologies and reduction of photodegradation \ncaused by UV high energy photons. Nanoparticles using \noptically active trivalent lanthanide ions (Ln3+)…
Silicon quantum dots are the subject of much research in the photovoltaic sector because of the ability to tune their bandgap. This makes them interesting for applications in a series of solar cell designs. There are many different ways to produce quantum dots, each having its own strengths and weaknesses. In this res…
Ceramic integration technologies enable hierarchical design and manufacturing of intricate ceramic and composite parts starting with geometrically simpler units that are subsequently joined to themselves and/or to metals to create components with progressively higher levels of complexity and functionality. However, fo…
Mobilité de sondes moléculaires des polyéthylèneglycols et des dendrimères mesurée par RMN dans des suspensions et des gels de caséine L'objectif de ce travail était d'étudier l'influence qu'exerce la microstructure des caséines sur la diffusion moléculaire de petites sondes ayant des tailles et des déformabilités dif…
Cette étude a été motivée par les nombreux avantages du procédé de micromoulage, qui couple la croissance électrolytique et la localisation du film avec un moule en résine épaisse. Ce procédé permet en effet la réalisation de micro-objets, dont les dimensions sont uniquement dépendantes de la résolution des techniques…
Simulations moléculaires d'une nouvelle classe de liquides ioniques basés sur la fonction ammonium pour l'utilisation potentielle en tant qu'huiles lubrifiantes respectueuses de l'environnement L'objectif de ce travail est de comprendre la structure et les interactions des liquides ioniques au contact de surfaces méta…
Several studies reported fenretinide (4-HPR) can be used as antitumoral drug in many types of cancer cell lines such as neuroblastoma, mammary carcinoma and melanoma. In vitro 4-HPR inhibits growth of neuroblastoma in a dose dependent manner with an high antitumor activity at 5–10 μM (Ponzoni et al., 1995).The main di…
The challenge to guide and control stem cell fate has been addressed in multiple ways by researchers, making it self-evident that biomedical nanodevices can play a key role in regenerative medicine. This includes the development of nanomaterials which are chemically and/or physically active and the joint capability of…
We are currently developing innovative methodologies for rapid prototyping of threedimensional (3D) replicas of the vascular matrix of soft and hard tissue organs, primarily the thyroid and bones, with the intent of obtaining organomorphic scaffolds for their ex situ reconstruction (1, 2). To identify biocompatible ma…
Autologous nerve grafting is considered the gold standard for bridging nerve lesion, although in several cases the use of artificial tubular guides is needed. Nowadays, the research is addressed to identify the ideal treatment able to support complete nerve regeneration and functional recovery. Therefore, the use of a…
Crimps are a typical feature of tendons and of some ligaments where they are responsible for the non-linear behaviour of the tissue at low strain values. Previous studies (Raspanti et al., 2005) shown that in tendons these visible crimps always correspond to a distinctive buckling and/or left-handed torsion of the col…
The aim of this study was to combine gelatin and ascorbic acid to produce a scaffold with antitumoral properties. Gelatin was chosen because is a derivative of collagen, the major constituent of skin, bones and connective tissues, and because it does not exhibit antigenicity. Ascorbic acid had been reported for many y…
Highly biocompatible polylactic acid (PLA)-derived polymers are used for different biomedical applications such as orthopaedic screws and drug delivery devices. Nevertheless their clinical use is limited by their proinflammatory characteristics. Vitamin E (α-tocopherol, Vit. E), a natural antioxidant and anti-inflamma…
Although autologous vascular grafts and artificial materials have been used for reconstruction of small diameter (<5mm) blood vessels, the poor availability of vessels and the occurrence of intimal hyperplasia and progressive atherosclerotic degeneration represent shortcomings of these vascular prostheses. Therefore,…
Ossicular chain (OC) is the bony part of middle ear dedicated to sound transmission. Chronic inflammations, infections and traumas occurring in the lifespan result in a set of severe diseases known as “conductive hearing loss”. To recover an acceptable hearing threshold, the damaged OC have to be surgically replaced w…
This work aimed to validate the efficacy of a tissue engineered osteochondral composite for the treatment of cartilage lesion produced in adult pigs. The osteochondral composite was manufactured by combining an osteo-compatible cylinder and a neocartilagineous tissue obtained by seeding swine articular chondrocytes in…
Gelatin is a denatured collagen and commercially available as a biodegradable polymer. It has been extensively utilized for pharmaceutical and medical purposes, and its biosafety has been proven through long clinical applications. It showed an high cell attachment and proliferation, thus it has been widely considered…