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Mechanistic analysis of solute transport in an in vitro physiological two‐phase dissolution apparatus

Peter Langguth、Patrick Marroum2012-10-01Deep Blue (University of Michigan)

In vitro dissolution methodologies that adequately capture the oral bioperformance of solid dosage forms are critical tools needed to aid formulation development. Such methodologies must encompass important physiological parameters and be designed with drug properties in mind. Two‐phase dissolution apparatuses, which…

Metallurgy and Material ScienceCrystallization and Solubility StudiesAgriculture, Soil, Plant Science

Lactosylated liposomes for targeted delivery of doxorubicin to hepatocellular carcinoma

Robert J Lee、Robert J Lee、Zhang 等 7 位作者2012-10-01International Journal of Nanomedicine

BACKGROUND: N-lactosyl-dioleoylphosphatidylethanolamine (Lac-DOPE) was synthesized and evaluated as a liver-specific targeting ligand via asialoglycoprotein receptors for liposomal delivery of doxorubicin. METHODS: Lactosylated liposomes encapsulating calcein (Lac-L-calcein) or doxorubicin (Lac-L-DOX) composed of egg…

Protease and Inhibitor MechanismsNanoparticle-Based Drug DeliveryAdvanced Drug Delivery Systems

Synthesis and Characterization of Carbon Nanospheres from Hydrocarbon Soot

Anu N. Mohan、B. Manoj2012-10-01International Journal of Electrochemical Science

Foreseeing the upcoming era of the carbon nanomaterials and their revolutionary applications, we have identified and explored the structural parameters of five effective precursors of the same -carbon black, soot obtained by the thermal decomposition of kerosene, diesel, paraffin wax and lubricant oil. Micro- Raman sp…

Diamond and Carbon-based Materials ResearchFullerene Chemistry and ApplicationsCarbon Nanotubes in Composites

Formation of Cr23C6 during the Sensitization of AISI 304 Stainless Steel and its Effect to Pitting Corrosion

Mohd Warikh Abd Rashid、Miron Gakim、Zulkifli Mohd Rosli 等 4 位作者2012-10-01International Journal of Electrochemical Science

The metallic carbide precipitation was observed after the sensitization of AISI 304 stainless steel specimens in neutral flame by using oxy-fuel and slowly cooled in the air. Correlation between corrosion and X-Ray Diffraction (XRD) shows that the enrichment of Cr23C6 in the microstructure of AISI 304 worsens the pitt…

High-Temperature Coating BehaviorsNuclear Materials and PropertiesHydrogen embrittlement and corrosion behaviors in metals

Physics and chemistry of layered chalcogenide superconductors

Keita Deguchi、Yoshihiko Takano、Yoshikazu Mizuguchi2012-10-01Science and Technology of Advanced Materials

Structural and physical properties of layered chalcogenide superconductors are summarized. In particular, we review the remarkable properties of the Fe-chalcogenide superconductors, FeSe and FeTe-based materials. Furthermore, we introduce the recently discovered BiS2-based layered superconductors and discuss their pro…

Iron-based superconductors research

Effects of icosahedral phase formation on the microstructure and mechanical improvement of Mg alloys: A review

Daokui Xu、En–Hou Han2012-10-01Progress in Natural Science Materials International

Icosahedral phase (I-phase) is a relatively excellent strengthening phase in Mg alloys. Depending on their volume fraction, the yield strength of Mg–Zn–Y–Zr alloys can vary from 150 to 450 MPa at room temperature. Recently, the formation of I-phase has been considered as one of the most effective methods for developin…

Magnesium Alloys: Properties and ApplicationsAluminum Alloy Microstructure PropertiesAluminum Alloys Composites Properties

Hysteresis effects in the inverse magnetocaloric effect in martensitic Ni-Mn-In and Ni-Mn-Sn

Ivan Titov、M. Acet、Michael Farle 等 7 位作者2012-10-01Journal of Applied Physics

The presence of a large inverse magnetocaloric effect around the martensitic transformation in Ni-Mn-Sn and Ni-Mn-In alloys is expected to lead to substantial cooling on applying a magnetic field. However, the occurrence of hysteresis around the transition causes limitations on adiabatic temperature-changes. We study…

Magnetic and transport properties of perovskites and related materialsHigh Entropy Alloys StudiesShape Memory Alloy Transformations

Active Control of Ferroelectric Switching Using Defect‐Dipole Engineering

Daesu Lee、Byung Chul Jeon、Seung‐Hyub Baek 等 10 位作者2012-10-01Advanced Materials

Active control of defect structures and associated polarization switching in a ferroelectric material is achieved without compromising its ferroelectric properties. Based on dipolar interaction between defect dipole and polarization, the unique functionality of the defect dipole to control ferroelectric switching is v…

Acoustic Wave Resonator TechnologiesFerroelectric and Piezoelectric MaterialsMultiferroics and related materials

MODIFIED ROMANOVSKY ALGORITHM FOR QUICK FINDING OF APPROXIMATE SOLUTION TO HOMOGENEOUS ALLOCATION PROBLEM

Rudolf A. Neydorf、Artem A. Zhikulin2012-10-01Advanced Engineering Research

The modification of Romanovsky algorithm for the approximate solution to the homogeneous allocation problem is developed. The modification involves lower resource requirements as against the original algorithm. The changes in the original algorithm which permit to provide a more effective procedure of loading executor…

LIFE-DEATH PROBLEM IN CULTURE OF PRE-INDUSTRIAL SOCIETY

Anna S. Lycheva2012-10-01Advanced Engineering Research

Attitude towards life - death during the antiquity and in the Middle Ages is considered. The comparative analysis of these phases of history is given. The author presents a number of reasons to explain the established attitude towards life and death in the given cultures.

MATHEMATICAL PREDICTION MODEL OF ELECTROMAGNETIC FIELD IMPACT ON OPERATION STABILITY OF RADIAL BEARING WORKING ON CONDUCTING GAS LUBRICATION

Kamil S. Akhverdiyev、Elena O. Lagunova、Konstantin A. Vaneyev2012-10-01Advanced Engineering Research

The technique of the hydrodynamic calculation of the gasdynamic journal bearing working on the conducting gas lubrication is presented. The analytical prediction problem on the friction bearing operation stability is solved. The assessment of the effect of Hartmann number, the gas compressibility parameter, and the el…

TENDER SYSTEM DEVELOPMENT IN CONSTRUCTION INDUSTRY

Anastasia S. Dudnik2012-10-01Advanced Engineering Research

Approaches to the tender system development by the example of introducing the computer program which provides the anticorruption component of the construction market activities are formulated.

“INNOVATION CHAOS” IN TRANSITIVE SOCIETY (SOCIOCULTURAL ANALYSIS)

Oleg M. Shtompel2012-10-01Advanced Engineering Research

Innovation processes in the modern society are considered from the sociocultural point of view. Some crisis phenomena (such as archaicism of culture) occurring under the “innovation chaos” conditions in the changeable socium are defined.

ENVIRONMENT IN THE AGGREGATE WITH SUBSYSTEMS OF REGIONAL ECONOMY

Gennady A. Babkov、Andrey E. Safronov2012-10-01Advanced Engineering Research

The essence, combination, and interaction of the regional economy subsystems are considered. The environment subsystem is distinguished as the basic one. The block of indicators characterizing one or another subsystem is revealed. The key indicators are selected from the block, and on their basis, the economies of the…

INNOVATION TRANSFER PROCESS IN INTEGRATED STRUCTURES OF HIGHER VOCATIONAL EDUCATION

Mikhail A. Izotov2012-10-01Advanced Engineering Research

The definition of the "knowledge economy" category is given. The place and role of the innovation transfer process in the knowledge economy is defined. The content of the "innovation firm" concept is revealed. It is proved that the importance of the innovative-active enterprises increases in the higher vocational educ…

FINITE-ELEMENT MODELING OF CONTAMINATION MASS TRANSFER PROCESSES IN TECHNOLOGICAL ENVIRONMENT WITH REGARD TO AIRFLOW TURBULENCE

Besarion C. Meskhi、Arkady N. Solovyev、Yury I. Bulygin Yury I. 等 4 位作者2012-10-01Advanced Engineering Research

The possibility of determining the air motion fields, temperatures, and the concentrations of harmfu l substances, based o n the finite - element simulation of the pollution mass transfer processes in the occupational environment with regard to the air flow turbulence is studied.