Materials Literature
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BACKGROUND: Multidrug resistance, a major impediment to successful cancer chemotherapy, is the result of overexpression of ATP-binding cassette (ABC) transporters extruding internalized drugs. Silencing of ABC transporter gene expression with small interfering RNA (siRNA) could be an attractive approach to overcome mu…
In Antarctica microorganisms are exposed to several conditions that trigger the generation of reactive oxygen species, such as high UV radiation. Under these conditions they must have an important antioxidant defense system in order to prevent oxidative damage. One of these defenses are pigments which are part of the…
The properties of Josephson junctions with a barrier made of a PdFe weakly ferromagnetic alloy with an iron content of about 1 at % have been studied. It has been shown that this alloy is a weak ferromagnet with a Curie temperature of 10–15 K in the required thickness range of 30–50 nm. The effect of the domain struct…
In capacitance-voltage (C-V) measurements, frequency dispersion in high-k dielectrics is often observed. The frequency dependence of the dielectric constant (k-value), that is the intrinsic frequency dispersion, could not be assessed before suppressing the effects of extrinsic frequency dispersion, such as the effects…
Abstract Threshold voltage shifts of a‐IGZO TFTs on plastics against bias‐temperature stress were successfully reduced below 0.03 V, equivalent to those on glass substrates. We have developed an 11.7‐inch qHD (960xRGBx540) flexible bottom‐emission active‐matrix organic light‐emitting diode (AMOLED) driven by a‐IGZO TF…
Ethanol intake can lead to an unexpected and possibly problematic increase in the bioavailability of druglike compounds. In this work we investigated the effect of ethanol on the apparent solubility and dissolution rate of poorly soluble compounds in simulated intestinal fluid representing a preprandial state. A serie…
This work revisits the design of crossbar and high-radix interconnects in light of advances in circuit and layout techniques that improve crossbar scalability, obviating the need for deep multi-stage networks. We employ a new building block, the Swizzle-Switch-an energy and area-efficient switching element that can re…
A family of pyrrolo[3,4-c]pyrrol-1(2H)-one (PPO) and 2,5-diazapentalene (DAP) chromophores and DAP-containing polymers were synthesized, and their optical and electrochemical properties were studied. PPO and DAP chromophores are readily obtained by chemical transformation of the lactam unit in diketopyrrolopyrrole (DP…
Low pH cement systems for encapsulating legacy nuclear industry wastes containing aluminium metal are being developed using blends of MgO and silica fume (SF). The rheology of the binary system is significantly improved by addition of sodium hexa-metaphosphate (Na-HMP) which reduces the required w/s ratio. The additio…
Abstract This article outlines the selection criteria for choosing an implant material for biomedical devices in orthopedic, dental, soft-tissue, and cardiovascular applications. It details the development of various implants, such as metallic, ceramic, and polymeric implants. The article discusses specific problems a…
Carbon nano-onions, as a newly-emergent member of the carbon family, have attracted attention in its both dry and wet applications. Here we report in vivo effects of water-soluble carbon nano-onions (wsCNOs) introduced in common food web of two model organisms: unicellular Escherichia coli (E. coli) and multicellular…
The size-dependent interaction of anionic silica nanoparticles with ionic (anionic and cationic) and nonionic surfactants has been studied using small-angle neutron scattering (SANS). The surfactants used are anionic sodium dodecyl sulfate (SDS), cationic dodecyltrimethyl ammonium bromide (DTAB), and nonionic decaoxye…
In this paper are presented information about common and advanced materials used for manufacturing of products by Fused Deposition Modelling (FDM) rapid prototyping technology. In different rapid prototyping technologies the initial state of material can come in either solid, liquid or powder state. In solid state it…
BACKGROUND: Understanding how nanomaterials are distributed in the body after exposure is important for assessing whether they are safe. In this study, we investigated the behavior and accumulation of nanoscaled and submicron-scaled zinc oxide (ZnO) particles in the body using optical imaging following oral exposure.…
Three types of MnO2 nanostructures, viz., α-MnO2 nanotubes, hollow β-MnO2 bipyramids, and solid β-MnO2 bipyramids, have been synthesized via a simple template-free hydrothermal method. Cyclic voltammetry and galvanostatic charge/discharge measurements demonstrate that the hollow β-MnO2 bipyramids exhibit the highest s…
Amyloid fibrils are β-sheet-rich protein aggregates commonly found in the organs and tissues of patients with various amyloid-associated diseases. Understanding the structural organization of amyloid fibrils can be beneficial for the search of drugs to successfully treat diseases associated with protein misfolding. Th…
Diatoms are important primary producers in the marine ecosystem. Currently it is difficult to genetically transform diatoms due to the technical limitations of existing methods. The promoter/terminator of the nitrate reductase gene of the model diatom Phaeodactylum tricornutum was cloned and used to drive chlorampheni…
BACKGROUND: Detection of the human epididymis secretory protein 4 (HE4) biomarker plays an important role in the early diagnosis of ovarian cancer. This study aimed to develop a novel localized surface plasmon resonance (LSPR) biosensor for detecting HE4 in blood samples from patients with ovarian cancer. METHODS: Sil…
BACKGROUND: The development of nonviral gene delivery systems is one of the most intriguing topics in nanomedicine. However, despite the advances made in recent years, several key issues remain unsettled. One of the main problems relates to the difficulty in designing nanodevices for targeted delivery of genes and oth…
Alteration of the topological order by band inversion is a key ingredient of a topologically nontrivial material. Using first-principles calculations for HgTe, PtScBi, and Bi${}_{2}$Se${}_{3}$, we argue that it is not accurate to ascribe the band inversion to the spin-orbit coupling. Instead, scalar relativistic effec…