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Intrinsic Dissolution as a Tool for Evaluating Drug Solubility in Accordance with the Biopharmaceutics Classification System

Michéle Georges Issa、Humberto Gomes Ferraz2011-01-01Dissolution Technologies

The Biopharmaceutics Classification System (BCS) is a tool that was created to categorize drugs into different groups according to their solubility and permeability characteristics. Through a combination of these factors and physiological parameters, it is possible to understand the absorption behavior of a drug in th…

Drug Solubulity and Delivery SystemsProtein purification and stabilityCrystallization and Solubility Studies

Adsorption of core-shell nanoparticles at liquid–liquid interfaces

Lucio Isa、Esther Amstad、Konrad Schwenke 等 7 位作者2011-01-01Soft Matter

The use of nanoparticles as building blocks for the self-assembly of functional materials has been rapidly increasing in recent years. In particular, two-dimensional materials can be effectively self-assembled at liquid interfaces thanks to particle localization and mobility at the interface in combination with tailor…

Surfactants and Colloidal SystemsPolymer Surface Interaction StudiesPickering emulsions and particle stabilization

Room temperature photo-induced phase transitions of VO2 nanodevices

Jyh Ming Wu、Lian Bang Liou2011-01-01Journal of Materials Chemistry

We have successfully fabricated VO2 nanodevices using a photo-induced phase transition mechanism under an ultraviolet-light (λ = 365 nm, I = 7 μW cm−2). On the obtained VO2 nanowires, the photo-induced insulator-to-metal (IM) phase transition occurred from monoclinic (insulator or semiconductor) to tetragonal (metal)…

Gas Sensing Nanomaterials and SensorsTransition Metal Oxide NanomaterialsGa2O3 and related materials

Multimodality and nanoparticles in medical imaging

Wen-Yen Huang、Jason J. Davis2011-01-01Dalton Transactions

A number of medical imaging techniques are used heavily in the provision of spatially resolved information on disease and physiological status and accordingly play a critical role in clinical diagnostics and subsequent treatment. Though, for most imaging modes, contrast is potentially enhanced through the use of contr…

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranosticsLanthanide and Transition Metal Complexes

Controlled synthesis of magnetic iron oxides@SnO2 quasi-hollow core–shell heterostructures: formation mechanism, and enhanced photocatalytic activity

Wei Wu、Shaofeng Zhang、Feng Ren 等 6 位作者2011-01-01Nanoscale

Iron oxide/SnO(2) magnetic semiconductor core-shell heterostructures with high purity were synthesized by a low-cost, surfactant-free and environmentally friendly hydrothermal strategy via a seed-mediated method. The morphology and structure of the hybrid nanostructures were characterized by means of high-resolution t…

Advanced Photocatalysis TechniquesZnO doping and propertiesCopper-based nanomaterials and applications

Production and Characterization of Cellulose Nanofibers from Wood Pulp

Nazia Siddiqui、Ryan H. Mills、Douglas J. Gardner 等 4 位作者2011-01-01Journal of Adhesion Science and Technology

Cellulose nanofibers with a size range of 5–100 nm have the potential to be a low cost renewable material that has application in a range of products. However, current chemical methods to produce crystalline nanofibers suffer from low yields and high chemical costs, while mechanical methods require high energy costs.…

Nanocomposite Films for Food PackagingAdvanced Cellulose Research StudiesLignin and Wood Chemistry

The role of defect chemistry in strontium titanates utilised for high temperature steam electrolysis

George Tsekouras、John T. S. Irvine2011-01-01Journal of Materials Chemistry

The significant role of perovskite defect chemistry brought about by the A-site doping of strontium titanate with lanthanum on high temperature steam electrolysis properties is demonstrated. Solid oxide electrolysis cells based on oxygen-excess La0.3Sr0.7TiO3+δ, A-site-deficient La0.2Sr0.7TiO3 and undoped SrTiO3 perov…

Advancements in Solid Oxide Fuel CellsMagnetic and transport properties of perovskites and related materialsElectronic and Structural Properties of Oxides

pH-triggered block copolymer micelles based on a pH-responsive PDPA (poly[2-(diisopropylamino)ethyl methacrylate]) inner core and a PEO (poly(ethylene oxide)) outer shell as a potential tool for the cancer therapy

Fernando C. Giacomelli、Petr Štěpánek、Cristiano Giacomelli 等 7 位作者2011-01-01Soft Matter

The potential of a novel pH-triggered block copolymer as a promising drug delivery platform for the cancer therapy has been explored. The block copolymer poly(ethylene oxide)-b-poly(glycerol monomethacrylate)-b-poly[2-(diisopropylamino)ethyl methacrylate] herein referred to as PEO113-b-PG2MA30-b-PDPA50 upon dissolutio…

Nanoparticle-Based Drug DeliveryAdvanced Polymer Synthesis and CharacterizationPolymer Surface Interaction Studies

Functionalized mesoporous silica supported copper(ii) and nickel(ii) catalysts for liquid phase oxidation of olefins

Mahasweta Nandi、Partha Roy、Hiroshi Uyama 等 4 位作者2011-01-01Dalton Transactions

Highly ordered 2D-hexagonal mesoporous silica has been functionalized with 3-aminopropyltriethoxysilane (3-APTES). This is followed by its condensation with a dialdehyde, 4-methyl-2,6-diformylphenol to produce an immobilized Schiff-base ligand (I). This material is separately treated with methanolic solution of copper…

Mesoporous Materials and CatalysisPolyoxometalates: Synthesis and ApplicationsOxidative Organic Chemistry Reactions

In situ modification of cellulose paper with amino groups for catalytic applications

Hirotaka Koga、Takuya Kitaoka、Akira Isogai2011-01-01Journal of Materials Chemistry

Amino groups were successfully introduced to cellulose paper using a silane coupling technique, through the condensation reaction between Si–OH of the organofunctional silane coupling agent and C–OH of cellulose. The as-prepared paper material, denoted amine-modified paper, had excellent handling convenience and some…

Advanced Cellulose Research StudiesAdvanced Data Storage TechnologiesLignin and Wood Chemistry

Magnetically separable BiFeO3 nanoparticles with a γ-Fe2O3 parasitic phase: controlled fabrication and enhanced visible-light photocatalytic activity

Renqing Guo、Liang Fang、Wen Dong 等 5 位作者2011-01-01Journal of Materials Chemistry

A facile sol–gel approach with a fixed calcination temperature is developed to prepare BiFeO3 (BFO) nanoparticles, and the gel-drying temperature is adjusted to control the appearance of a γ-Fe2O3 parasitic phase. The room temperature ferromagnetism of the samples is strongly dependent on the gel-drying temperature. W…

Multiferroics and related materialsIron oxide chemistry and applicationsTeratomas and Epidermoid Cysts

Facile synthesis of 3D boron nitride nanoflowers composed of vertically aligned nanoflakes and fabrication of graphene-like BN by exfoliation

Gang Lian、Xiao Zhang、Miao Tan 等 6 位作者2011-01-01Journal of Materials Chemistry

Here, we present a facile solid phase method for preparing unique, 3D hexagonal boron nitride (hBN) nanoflowers, which are composed of vertically aligned BN nanoflakes. The growth process of BN nanoflowers is well-controlled by appropriately changing the reaction times and can be explained by a delayed-release mechani…

Graphene research and applications2D Materials and ApplicationsDiamond and Carbon-based Materials Research

Cancer Therapeutics- Opportunities, Challenges and Advances in Drug Delivery

Deepak Kakde、Rajendra Kakde、agadevappa Patil 等 5 位作者2011-01-01OpenAlex

This review highlights the characteristics of the cancer that provide opportunities for drug delivery carriers to target cancer. These opportunities include EPR effect, high interstitial pressure of tumour, low pH of endosomes of tumor cells, overexpressed receptors, angiogenesis etc. Chemotherapy is one of the most i…

Nanoparticle-Based Drug DeliveryRNA Interference and Gene DeliveryDendrimers and Hyperbranched Polymers

Polypropylene nanocomposites based on C60-decorated carbon nanotubes: thermal properties, flammability, and mechanical properties

Pingan Song、Liping Zhao、Zhenhu Cao 等 4 位作者2011-01-01Journal of Materials Chemistry

In the present study, the effects of covalently functionalized carbon nanotubes (CNTs) decorated with C60 (abbr. C60-d-CNT) on thermal, flame retardancy and mechanical properties of polypropylene (PP) are investigated. Compared with pristine CNTs, the C60-d-CNT is more easily dispersed in the PP matrix through reactiv…

Carbon Nanotubes in CompositesPolymer Nanocomposites and PropertiesFlame retardant materials and properties

Active Targeted Macrophage-mediated Delivery of Catalase to Affected Brain Regions in Models of Parkinson?s Disease

Yuling Zhao、Matthew J. Haney2011-01-01Journal of Nanomedicine & Nanotechnology

We previously demonstrated that monocyte-macrophage based drug delivery can be applied to a spectrum of infectious, neoplastic, and degenerative disorders. In particular, bone marrow-derived macrophages (BMM) loaded with nano formulated catalase, "nanozyme", were shown to attenuate neuro inflammation and nigrostriatal…

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration MechanismsAdvanced Nanomaterials in Catalysis

Three Techniques Used to Produce BaTiO<sub>3</sub> Fine Powder

Emad K. Al‐Shakarchi、Natheer B. Mahmood2011-01-01Journal of Modern Physics

Homogeneous BaTiO3 fine powder has been synthesized at (80°C) by using three different chemical methods using the roots TiCl4, BaCl2 and NaOH or Oxalic acid. The resultant powders were characterized using x-ray diffraction (XRD) to estimate the crystal structure, lattice parameters and the crystallite size to investig…

Ferroelectric and Piezoelectric MaterialsMicrowave Dielectric Ceramics SynthesisX-ray Diffraction in Crystallography

Electrospun Collagen: A Tissue Engineering Scaffold with Unique Functional Properties in a Wide Variety of Applications

Balendu Shekhar Jha、Chantal E. Ayres、James R. Bowman 等 7 位作者2011-01-01Journal of Nanomaterials

Type I collagen and gelatin, a derivative of Type I collagen that has been denatured, can each be electrospun into tissue engineering scaffolds composed of nano- to micron-scale diameter fibers. We characterize the biological activity of these materials in a variety of tissue engineering applications, including endoth…

Electrospun Nanofibers in Biomedical ApplicationsSilk-based biomaterials and applicationsTissue Engineering and Regenerative Medicine

Nanoporous gold: a new gold catalyst with tunable properties

Arne Wittstock、Andre Wichmann、J. Biener 等 4 位作者2011-01-01Faraday Discussions

Nanoporous gold (np-Au) represents a novel nanostructured bulk material with very interesting perspectives in heterogeneous catalysis. Its monolithic porous structure and the absence of a support or other stabilizing agents opens up unprecedented possibilities to tune structure and surface chemistry in order to adapt…

Electrocatalysts for Energy ConversionGold and Silver Nanoparticles Synthesis and ApplicationsNanoporous metals and alloys

Synthesis of carbon-supported Pt nanoparticle electrocatalysts using nanocrystalline cellulose as reducing agent

Lee Johnson、Wim Thielemans、Darren A. Walsh2011-01-01Green Chemistry

Pt nanoparticles have been synthesized at relatively low temperatures in aqueous solution from hexachloroplatinic acid using cellulose nanocrystals (CNXLs) from cotton as reducing agents. The Pt nanoparticles were characterised using X-ray diffraction, transmission electron microscopy, X-ray photoelectron spectroscopy…

Advanced Cellulose Research StudiesCopper-based nanomaterials and applicationsNanomaterials for catalytic reactions

A simple and scalable graphene patterning method and its application in CdSe nanobelt/graphene Schottky junction solar cells

Yu Ye、Lin Gan、Lun Dai 等 10 位作者2011-01-01Nanoscale

We have developed a simple and scalable graphene patterning method using electron-beam or ultraviolet lithography followed by a lift-off process. This method, with the merits of: high pattern resolution and high alignment accuracy, being free from additional etching or harsh processes, being universal to arbitrary sub…

Graphene research and applicationsQuantum Dots Synthesis And PropertiesNanowire Synthesis and Applications