Materials Literature
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Nowadays, the concept of quality by design (QbD) and more particularly the design space (DS) has become widespread in the field of pharmaceutical sciences. The ICH Q8(R2) guideline [1] defines the design space as “the multidimensional combination and interaction of input variables (e.g., material attributes) and proce…
new technique for carbon nanotube oxidation was developed based upon the photo-oxidation of organic compounds. The resulting method is more benign than conventional oxidation approaches and produces single-wall carbon nanotubes (SWCNTs) with higher levels of oxidation. In this procedure, an oxygen saturated suspension…
Electrochemical capacitors, also known as supercapacitors, are becoming increasingly important components in energy storage, although their widespread use has not been attained due to a high cost/ performance ratio. Fundamental research is contributing to lowered costs through the engineering of new materials. Current…
【背景と目的】生体吸収性材料を用いた心血管グラフトはグラフトの吸収とともに自己組織によって置換されるため, 既存の非吸収性グラフトで見られる不具合 (血栓閉塞, 感染, 成長能の欠如) を克服できる可能性がある. 本実験ではラット右室流出路再建モデルを用いて, エレクトロスピニング法で作製したポリ乳酸-ポリグリコール酸共重合体 (PLGA) ポリマーファイバーグラフトの組織適合性および移植後の組織の耐圧性につき検討した. 【方法】エレクトロスピニング法によりPLGA ポリマーファイバー不織布を紡糸しシート状のグラフトを作製した. ラット右室流出路に全層性の欠損を作製し同部を直径7mmの円形にトリミングしたグラフトを用いて再建した.…
2,6-Bis(porphyrin)-substituted 3,5-dimethylpyrazine and its zinc complex bound C 70 to yield 1:1 inclusion complexes, which were characterised by ESI-MS, UV-Vis, fluorescence, and NMR spectroscopies.Association constants of the C 70 complexes were determined by fluorescence and NMR spectral analyses.A decrease in abso…
平削り盤、形削り盤、立削り盤、ブロー チ盤、歯切り盤、歯車研削盤、歯車仕上
A funcionalidade de um tecido, de acordo com o dicionário, poderia definir-se como aquele desenho que busca a facilidade, utilidade e comodidade de seu uso. Segundo isto, um dos principais objectivos, ainda que não o único, da funcionalidade dos tecidos é o conforto. Para isso é importante que aislen termicamente do f…
The Australian Nuclear Science and Technology Organisation (ANSTO) operated the HIFAR research reactor from 1958 to 2007. During this period HIFAR produced radioactive discharges to the atmosphere which complied with regulatory licence conditions to operate the facility. Noble gases are released during the fission pro…
Hydroxyapatite is used in bone reconstruction because of its similar chemical structure compared to the inorganic composition of human bone. Bone is a complex material composed of proteins, mainly collagen, with hydroxyapatite. Therefore, now many investigations are focused on the hybrid biomaterials of hydroxyapatite…
To learn about the interaction between drug agents and nanoparticular carrier systems, the physical analytical methods of parelectric, electron spin and fluorescence spectroscopy have proven helpful tools to yield descriptive models of such complex systems. For a deeper understanding of drug absorption from body surfa…
In this work, PLGA nanoparticles were prepared by an emulsification-diffusion technique. The main objective was to optimize the preparation of formulations by evaluating the influence of the technological parameters on the physicochemical properties of PLGA nanoparticles. The effects of variations in polymer and emuls…
灌流培養環境下でHL60細胞とI型コラーゲンとの相互作用を観察するため, poly (dimethylsiloxane)を用いて微小流路デバイス(幅700μm×高さ100μm×長さ20mm)を作製した. 矩形断面を有する微小流路内壁4面すべてを酸素プラズマ処理し, ニワトリI型コラーゲンとウシ胎児血清成分タンパク質を灌流して固定化した. 固定化されたタンパク質の吸着量をSDS-ポリアクリルアミドゲル電気泳動にて定量的に調べた結果, 血清タンパク質に対して酸素プラズマ処理の効果は認められなかったが, I型コラーゲンでは酸素プラズマ処理の効果が経時的に減少するに従い, その固定化量が増加した. 作製した微小流路デバイスを用いた0.2μ…
A printing plate for gravure printing consisting of five layers of aluminum alloy / anodic oxide film / nickel / polypyrrole / copper was fabricated by anodizing, electro-less plating, electroplating, and electro-polymerization. Nickel layers were first deposited on anodic oxide film-covered aluminum alloy by electro-…
The surface structure of polycrystalline wustite was observed by means of scanning tunnel microscopy (STM). Wustite (Fe1-xO) samples were prepared from oxidation of iron plates under different oxygen partial pressures. The non-stoichiometry numbers (1-x) of Fe1-xO were 0.912, 0.901 and 0.887, respectively. Fe1-xO surf…
ヌアスムグリ アリマス，高橋修平，榎本浩之，中村文彬(北見工業大学) ， 金 籠元
Diffusional creep of a polycrystal with bimodal grain-size distribution is examined with spherical-grain approximation. Deformation behavior and stress states of the polycrystal are formulated when grain-boundary sliding occurs much more rapidly than diffusion. Two distinct effects of the grain-size distribution are d…
Le sujet de la thèse a été orienté vers trois axes majeurs : l'étude de la photochimie des aldéhydes et de leur capacité à photoamorcer une polymérisation radicalaire, l'étude des aldéhydes en tant qu'amorceurs thermiques, avec l'étude des interactions entre des aldéhydes et des sels métalliques ou des sels d'iodonium…
[[abstract]]本研究主要針對拼接式四邊形抗彈陶瓷靶板與拼接式六邊形抗彈陶瓷靶板其抗彈性能之差異。比較在不同厚度下，四邊形靶板和六邊形靶板抗彈性能之差異，及添加厚度6.3mm之背層板（鋁板）後，其抗彈性能提升效率。利用有限元素軟體LS-DYNA進行模擬，並分析子彈貫穿靶板時之能量傳遞方式及子彈殘餘末速度。由研究結果得知，拼接式六邊形靶板其能量傳遞效果優於拼接式四邊形靶板，而添加背層板（銘板）後， 抗彈性能也優於拼接式四邊形靶板。 This study aimed bullet-proof ceramic mosaic-style quadrangle with the stitching anvil-type hexago…
[[abstract]]本研究利用不同比例的熱致變色材，四氯銅雙二乙基銨鹽添加聚醋酸乙烯酯製成薄膜乾燥後，測試在一般室溫下的溫度和高溫下的透光率變化。由實驗研究得知，熱致變色薄膜隨著溫度升高，透光率成反比下降。本實驗依重量百分濃度採用的五種比例，在透光率方面以依重量百分濃度添加1.0%四氣銅雙二乙基銨鹽之聚醋酸乙烯酯薄膜，為採用五種比例中透光率最低，但在測量室溫和高溫比較下，0.5%相較下的差異性最大。考量到相差值方面，依重量百分濃度添加0.5%四氣銅雙二乙基銨鹽的聚醋酸乙烯酯薄膜為優先考量。 In this study, different proportions of thermochromic material tetrac…
[[abstract]]本研究嘗試發展一種其生物可分解性的膠囊，應用於液態肥料制放之用途。探討不同製備參數下膠囊的分解時間、粒徑變化及最佳去乙醯化度。並運用最佳化的製備參數之樣本，在酸鹼值5.5下以溶菌酶進行酵素分解與肥料制放之探討。結果顯示，在電導度（EC）測試中，雙殼材的膠囊樣本，緩釋效果比幾丁聚醣膠囊平均下降0.69%，幾丁聚醣膠囊若加上丙酮脫水處理，則可得到更佳緩釋效果，結果較幾丁聚醣樣本平均下降2.42% ，證實可提高緩釋性的效果。而雙殼材的膠囊樣本，其緩釋效果比幾丁聚醣膠囊平均下降2.66%，樣本再以丙酮脫水處理後，可得到更佳緩釋效果，較幾丁聚醣樣本平均下降4.62%。 ln this research, we dev…