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Vascular Targeting of Brain Tumors – Bridging the Gap with Phage Display

Michael G. Ozawa、Fernanda I. Staquicini、Richard L. Sidman 等 5 位作者2009-01-01Humana Press eBooks

The development of targeted therapies for cancer remains an enormous challenge. Despite advances in the understanding of molecular pathways involved in tumor growth and rational design of new agents, a gap exists between drug development and patient survival. Ligand-directed delivery of drugs to the tumor is one appro…

Nanoparticle-Based Drug DeliveryGlycosylation and Glycoproteins ResearchMonoclonal and Polyclonal Antibodies Research

Selective Separation and Recovery of Actinoid by Ion-Exchange Methods

Hitoshi Mimura、Isao Yamagishi2009-01-01Journal of Ion Exchange

先進的再処理・放射性廃棄物処理においてはアクチノイド核種の選択的分離回収技術の高度化が重要な課題とされている。長寿命核種の核変換処理のための第一のステップであり,さらに核不拡散および廃棄物処分の負担軽減,環境負荷低減および資源化・有効利用の観点からも高度分離技術の開発は期待されている。イオン交換技術は,アクチノイド分離の先駆的な技術と位置づけられており,基礎的に選択性を評価するとともに,実用化に向けたイオン交換プロセスの合理化や簡素化の研究が各国で精力的に展開されている。近年より精密な核種分離手法の開発に期待がかけられており,選択的なイオン交換技術の高度化は極めて重要な意義を有している。 本報では,(1)アクチノイド分離の目的と効…

Radioactive element chemistry and processingNuclear materials and radiation effectsChemical Synthesis and Characterization

Rule Inducted Models for Classifying Water Quality Using Diatoms as Bio-indicators

Andreja Naumoski、Kosta Mitreski2009-01-01OpenAlex

In this paper we use the property of diatoms as bioindicators, to indentify which WQC is the taken sample using machine learning classifying algorithm - CN2. Important physical-chemical parameters such as conductivity, saturated oxygen and mostly used pH have defined range in which water class they belong. These physi…

Diatoms and Algae ResearchWater Quality Monitoring TechnologiesWater Quality Monitoring and Analysis

Effect of effective viscosity on characteristics of microscale gas journal bearings

Haijun Zhang、Changsheng Zhu、Qin Yang2009-01-01OpenAlex

According to 1st order slip velocity boundary, modified Reynolds equation for microscale gas journal bearings is presented with consideration of effective viscosity of gas under rarefied condition. Modified Reynolds equation is solved using the finite difference method. Non-dimensional pressure distribution, load capa…

Diamond and Carbon-based Materials ResearchGas Dynamics and Kinetic TheoryVacuum and Plasma Arcs

Effects of Peg Additives on Water Vapor Permeability of Porous PVDF Membranes

Li‐Zhi Zhang、Lixia Pei2009-01-01OpenAlex

Porous polyvinylidene fluoride (PVDF) membranes with various structures were prepared via phase inversion using DMF as solvent. Polyethylene glycols (PEG) with three different concentrations and molecular weights were used. Effects of PEG on the structure and performance of porous membranes were investigated. The morp…

Surface Modification and SuperhydrophobicityAdvanced Sensor and Energy Harvesting Materials

Quantification of the RELAP5 Model Uncertainty for Application to the Loss-of-RHR Event During the Mid-Loop Operation

Ikuo Kinoshita、Hiroichi Nagumo、Minoru Yamada 等 5 位作者2009-01-01Volume 2: Structural Integrity; Safety and Security; Advanced Applications of Nuclear Technology; Balance of Plant for Nuclear Applications

Best estimate analysis method for the loss of Residual Heat Removal (loss-of-RHR) event during the mid-loop operation is being conducted along the Code Scaling, Applicability and Uncertainty (CSAU) evaluation methodology. The analysis method uses RELAP5/MOD3.2 as a best estimate analysis code. One of the important pro…

Nuclear reactor physics and engineeringNuclear Materials and PropertiesNuclear Engineering Thermal-Hydraulics

The effect of boron on the abrasive wear behavior of austenitic Febase hardfacing alloys

Ki Nam Kim、Myung Chul Park、Gyeong Su Shin 等 4 位作者2009-01-01ESOMAT 2009 - 8th European Symposium on Martensitic Transformations

The effect of boron on the abrasive wear behavior of the austenitic Fe-Cr-C-Si-B hardfacing alloys was investigated with varying boron concentration. It was found that the abrasive wear resistance of the hardfacing alloys increased up to 50% compared to that of boron free alloys with increasing boron concentration. Th…

Advanced materials and compositesTribology and Wear AnalysisMetal Alloys Wear and Properties

Engineering and Directed Evolution of a Ca2+ Binding Site A‐Deficient AprE Mutant Reveal an Essential Contribution of the Loop Leu75–Leu82 to Enzyme Activity

Eliel R. Romero-García、Alfredo Téllez‐Valencia、María F. Trujillo 等 8 位作者2009-01-01BioMed Research International

An aprE mutant from B. subtilis 168 lacking the connecting loop Leu(75)-Leu(82) which is predicted to encode a Ca(2+) binding site was constructed. Expression of the mutant gene (aprEDeltaLeu(75)-Leu(82)) produced B. subtilis colonies lacking protease activity. Intrinsic fluorescence analysis revealed spectral differe…

Bacterial Genetics and BiotechnologyCRISPR and Genetic EngineeringEnzyme Structure and Function

Ultrafast Carrier Dynamics in Exfoliated Graphene and Graphite

Ryan W. Newson、Jesse Dean、H. M. van Driel2009-01-01OpenAlex

We measure 150 fs time-resolved 800 nm pump/ 1300 nm probe differential reflectivity and transmissivity of graphitic samples, ranging from one (graphene) to >100 layers (graphite). Carrier cooling kinetics vary gradually with number of layers.

Diamond and Carbon-based Materials ResearchHigh voltage insulation and dielectric phenomenaForce Microscopy Techniques and Applications

A Superheated State in Granular Matter

F. Pacheco-Vázquez、Gabriel A. Caballero-Robledo、J. C. Ruiz‐Suárez 等 5 位作者2009-01-01AIP conference proceedings

We report the experimental observation of a superheated granular system: A vibrated hexagonal monolayer that persists as a crystal for some time until it spontaneously evaporates. We observe the nucleation sites of the gas and follow the dynamics of the evaporation, where mean lifetimes of the metastable state are obt…

Material Dynamics and PropertiesGranular flow and fluidized bedsAdvanced Thermodynamics and Statistical Mechanics

Energy Level Fine Structure of Cr[sup 3+] Doped in KMgF[sub 3] Crystal

Andrea Reisz、C.N. Avram、Mădălin Bunoiu 等 4 位作者2009-01-01AIP conference proceedings

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Andrea M. Reisz, Calin N. Avram; Energy Level Fine Structure of Cr3+ Doped in KMgF3 Crystal. AIP…

Luminescence Properties of Advanced MaterialsInorganic Chemistry and MaterialsInorganic Fluorides and Related Compounds

Soil gas Radon, Indoor Radon and Gamma Dose Rate in Tirana city, ALBANIA

S. Dogjani、L.L. Langore、O. Lika 等 4 位作者2009-01-015th Congress of Balkan Geophysical Society

During a 3 year period, the Natural Radioactivity Sector of the Geophysics Department has conducted radon concentration measurements in the soil and indoors in Tirana. The measurements have covered a 40 km2 area. Radon measurements have been made in 160 squares. In these 160 squares, we have made 2400 measurements of…

Radioactivity and Radon MeasurementsGraphite, nuclear technology, radiation studiesNuclear and radioactivity studies

B23 Effect of Sulfide Inclusion Morphology on Surface Roughness in Free Cutting Steel(Advanced machining technology)

Naoki Matsui、Junsuke FUJIWARA2009-01-01Proceedings of International Conference on Leading Edge Manufacturing in 21st century LEM21

In order to develop a new eco-friendly non-leaded free cutting steel, it is important to get good machinability by the use of manganese sulfide (MnS) inclusions in place of lead. In this study, the effect of MnS morphology on the surface roughness was assessed in a turning test used two steels containing different typ…

Advanced Surface Polishing TechniquesMetal Alloys Wear and PropertiesSurface Roughness and Optical Measurements

Effect of Tungsten Addition on the Nucleation of Borides in Wide Gap Brazed Joint

Daniel McGuire、Xiao Huang、Doug Nagy 等 4 位作者2009-01-01OpenAlex

Wide gap brazing (WGB) is a cost effective and reliable means to repair gas turbine hot section components with defect sizes exceeding 0.3 mm. However, it has been shown that WGB joints of nickel-based superalloys suffer from reduced ductility and thermal fatigue life due to the presence of brittle intermetallics and…

High Temperature Alloys and CreepIntermetallics and Advanced Alloy PropertiesMetal Alloys Wear and Properties

Sodium hydrogencarbonate (NaHCO3): coincidence-site lattice twinning and structure refinement

Michael E. Fleet、Xi Liu2009-01-01Zeitschrift für Kristallographie

Sodium hydrogencarbonate (NaHCO 3 ) has been recrystallised hydrothermally using a cooling ramp from 250 °C to 190 °C at 0.069 GPa, and investigated by single crystal X-ray diffraction at room temperature and pressure. Representative crystal data are: monoclinic, space group P 2 1 / n , Z = 4, a = 7.4688(4), b = 9.684…

Crystallography and molecular interactionsNonlinear Optical Materials ResearchSolid-state spectroscopy and crystallography

Diffraction angle prediction of surface micromachined planar curved grating and crossed grating

Kuan‐Yu Chen、Ju-Nan Kuo2009-01-01OpenAlex

In this study, the different curvature of surface micromachined planar curved grating is systematically investigated. The crossed grating with various pitches was also explored. The planar curved grating and crossed grating were fabricated using multi-user MEMS processes (MUMPs) provided by MEMSCAP Inc. The angular se…

Advanced MEMS and NEMS TechnologiesAdvanced Measurement and Metrology TechniquesOptical Coatings and Gratings

The Effect of Micro Dent Arrays Fabricated by Laser Shock Peening on Tribology

R. Caslaru、Y. B. Guo2009-01-01ASME/STLE 2009 International Joint Tribology Conference

Surface micro dents may act as lubricant reservoirs to reduce friction and wear in sliding and rolling contact applications. Surface patterning has become a valuable technique for fabricating micro dents. Alternative methods such as micromachining present obvious limitations in comparison with laser shock peening (LSP…

Diamond and Carbon-based Materials ResearchTendon Structure and TreatmentSurface Treatment and Residual Stress

NONEQUILIBRIUM VOLUMETRIC RESPONSE OF SHOCKED POLYMERS

B. E. Clements、Mark Elert、Michael D. Furnish 等 6 位作者2009-01-01AIP conference proceedings

Polymers are well known for their non-equilibrium deviatoric behavior. However, investigations involving both high rate shock experiments and equilibrium measured thermodynamic quantities remind us that the volumetric behavior also exhibits a non-equilibrium response. Experiments supporting the notion of a non-equilib…

Material Dynamics and PropertiesAdvanced Thermodynamics and Statistical MechanicsAdvanced Physical and Chemical Molecular Interactions

The Effects of Fracture Origin Size on Fatigue Properties of Ductile Cast Iron with Small Chill Structures

Daigo SAMESHIMA、Takashi Nakamura、Noritaka Horikawa 等 5 位作者2009-01-01Journal of Solid Mechanics and Materials Engineering

Reducing the weight of a machine structure is an increasingly important consideration both for the conservation of resources during production and for the energy saving during operation. With these objectives in mind, thin-walled ductile cast iron has recently been developed. Because rapid cooling could result in brit…

Microstructure and Mechanical Properties of SteelsMetallurgy and Material FormingMetal Alloys Wear and Properties